Database of 2256 Experimentally Validated Allergens

Data for Ara h 2
WHO/IUIS recognized Allergen

1  1  1  1  1  0  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
(Read More)


Download data as Text file

AllerBase IDAB_P_00173Allergen NameAra h 2
Source OrganismArachis hypogaea (Peanut)KingdomPlant
Biological Function/RoleProtease inhibitorMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Ara h 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Ara h 2.0101Conglutin-7
AY007229.1  (View Sequence)AAK96887.1  (View Sequence)Q6PSU2  (View Sequence)
--
Ara h 2.0201Conglutin-7AY158467.1  (View Sequence)AAN77576.1  (View Sequence)Q6PSU2  (View Sequence)
--

Sequence Analysis

  • BLAST
  • Pairwise alignment
  • Hide Tab

  • BLAST Nucleotide/Protein sequence of Allergen Ara h 2 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

    OR
    Set E-value of your choice:    

       


  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Ara h 2:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

    *

    *Input your Nucleotode or Protein sequence (in FASTA format) here:

        


Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome51
AllFamAF050

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Ara h 2Ara h 2.0101RDPYSPSQDPYSPSSequential / Linear62-75-157833IgE from Peanut-allergic patients---Western / Immunoblot21883278-
Ara h 2Ara h 2.0101HASARQQWELSequential / Linear18-27-23562IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101QWELQGDRSequential / Linear24-31-52829IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101DRRCQSQLERSequential / Linear30-39-10040IgE from serum of peanut allergic patients--Immunodominant epitopeWestern / Immunoblot9186485-
Ara h 2Ara h 2.0101LRPCEQHLMQSequential / Linear42-51-39156IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101KIQRDEDSSequential / Linear52-59-31404IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101RDPYSPSequential / Linear62-67-73754IgE from serum of peanut allergic patients--Immunodominant epitopeWestern / Immunoblot9186485-
Ara h 2Ara h 2.0101SQDPYSPSSequential / Linear68-75-60413IgE from serum of peanut allergic patients--Immunodominant epitopeWestern / Immunoblot9186485-
Ara h 2Ara h 2.0101LQGRQQSequential / Linear120-125-10012IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101KRELRNSequential / Linear130-135-33122IgE from serum of peanut allergic patients---Western / Immunoblot9186485-
Ara h 2Ara h 2.0101QRCDLDVESequential / Linear146-153-52191IgE from serum of peanut allergic patients---Western / Immunoblot9186485-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Ara h 2Ara h 6   (View AllerBase Entry)15836759
Ara h 2Lup an DCong  (View AllerBase Entry)
Lup an ACong  (View AllerBase Entry)
19639724
Ara h 2Ara h 3  (View AllerBase Entry)
Ara h 1  (View AllerBase Entry)
23465659
Ara h 2Ara h 1  (View AllerBase Entry)
Ara h 3  (View AllerBase Entry)
Ara h 6  (View AllerBase Entry)
25802736
Ara h 2Ara h 1  (View AllerBase Entry)
Ara h 3  (View AllerBase Entry)
30545888