References/Publications for Lymphocyte proliferation assay of Der p 1

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10768730 Pediatr Allergy Immunol. 2000 Feb;11(1):4-11.

Culture conditions for the detection of allergen-specific T-cell reactivity in
cord blood: influence of cell number.

Kopp MV(1), Pichler J, Halmerbauer G, Kuehr J, Frischer T, Urbanek R, Szépfalusi

12001789 Allergy Asthma Proc. 2002 Mar-Apr;23(2):109-15.

The effect of disodium cromoglycate, budesonide, and cyclosporin A on
interleukin-4, interleukin-5, and interleukin-13 secretions in Der p I-stimulated
T cells from house dust mite-sensitive atopic and nonatopic individuals.

Oh JW(1), Lee HB, Chung YH, Choi Y.

12569979 Clin Exp Allergy. 2002 Nov;32(11):1589-95.

T cell cytokine responses to outer membrane proteins of Haemophilus influenzae
and the house dust mite allergens Der p 1 in allergic and non-allergic subjects.

Epton MJ(1), Hales BJ, Thompson PJ, Thomas WR.

16181456 Br J Dermatol. 2005 Oct;153(4):750-7.

Relative impact of CD4+CD25+ regulatory T cells and tacrolimus on inhibition of
T-cell proliferation in patients with atopic dermatitis.

Vukmanovic-Stejic M(1), McQuaid A, Birch KE, Reed JR, Macgregor C, Rustin MH,
Akbar AN.

16393263 Clin Exp Allergy. 2006 Jan;36(1):32-9.

Absence of systemic immunologic changes during dose build-up phase and early
maintenance period in effective specific sublingual immunotherapy in children.

Dehlink E(1), Eiwegger T, Gerstmayr M, Kampl E, Bohle B, Chen KW, Vrtala S,
Urbanek R, Szépfalusi Z.

16499636 Clin Exp Allergy. 2006 Mar;36(3):261-72.

Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates
allergen-specific immunoglobulin E and increases both interferon-gamma- and

Cosmi L(1), Santarlasci V, Angeli R, Liotta F, Maggi L, Frosali F, Rossi O,
Falagiani P, Riva G, Romagnani S, Annunziato F, Maggi E.

18849611 Int Arch Allergy Immunol. 2009;148(3):199-210. doi: 10.1159/000161580. Epub 2008
Oct 10.

Insufficient increment of CD4+CD25+ regulatory T cells after stimulation in vitro
with allergen in allergic asthma.

Wang LH(1), Lin YH, Yang J, Guo W.

19159822 Immunobiology. 2009;214(1):2-16. doi: 10.1016/j.imbio.2008.04.006. Epub 2008 Jun

Allergen-driven suppression of thiol production by human dendritic cells and the
effect of thiols on T cell function.

Hasan AA(1), Ghaemmaghami AM, Fairclough L, Robins A, Sewell HF, Shakib F.

19226276 Clin Exp Allergy. 2009 May;39(5):760-70. doi: 10.1111/j.1365-2222.2009.03201.x.
Epub 2009 Feb 18.

Production of native and modified recombinant Der p 1 molecules in tobacco

Burtin D(1), Chabre H, Olagnier B, Didierlaurent A, Couret MN, Comeau D, Wambre
E, Laparra H, Van Overtvelt L, Montandon F, Batard T, Jonval V, Lorphelin A,
Merle C, Berrouet C, Parry L, Gomord V, Van Ree R, Moingeon P.

19400901 Clin Exp Allergy. 2009 Jul;39(7):1088-98. doi: 10.1111/j.1365-2222.2009.03264.x.
Epub 2009 Apr 21.

Engineering of major house dust mite allergens Der p 1 and Der p 2 for
allergen-specific immunotherapy.

Asturias JA(1), Ibarrola I, Arilla MC, Vidal C, Ferrer A, Gamboa PM, Vińuela JE,
Sanz ML, Andreu C, Martínez A.

19494500 Int Arch Allergy Immunol. 2009;149 Suppl 1:21-4. doi: 10.1159/000210649. Epub
2009 Jun 3.

Development of transgenic rice expressing mite antigen for a new concept of

Suzuki K(1), Kaminuma O, Yang L, Motoi Y, Takai T, Ichikawa S, Okumura K, Ogawa
H, Mori A, Takaiwa F, Hiroi T.

20153036 J Allergy Clin Immunol. 2010 Mar;125(3):727-36. doi: 10.1016/j.jaci.2009.12.004.
Epub 2010 Feb 11.

Induction of anergic allergen-specific suppressor T cells using tolerogenic
dendritic cells derived from children with allergies to house dust mites.

Pacciani V(1), Gregori S, Chini L, Corrente S, Chianca M, Moschese V, Rossi P,
Roncarolo MG, Angelini F.

20407270 Int Arch Allergy Immunol. 2010;153(2):141-51. doi: 10.1159/000312631. Epub 2010
Apr 21.

Recombinant fusion proteins assembling Der p 1 and Der p 2 allergens from
Dermatophagoides pteronyssinus.

Bussičres L(1), Bordas-Le Floch V, Bulder I, Chabre H, Nony E, Lautrette A,
Berrouet C, Nguefeu Y, Horiot S, Baron-Bodo V, Van Overtvelt L, De Conti AM,
Schlegel A, Maguet N, Mouz N, Lemoine P, Batard T, Moingeon P.

21447056 Plant Biotechnol J. 2011 Dec;9(9):982-90. doi: 10.1111/j.1467-7652.2011.00613.x.
Epub 2011 Mar 29.

Prevention of allergic asthma by vaccination with transgenic rice seed expressing
mite allergen: induction of allergen-specific oral tolerance without bystander

Suzuki K(1), Kaminuma O, Yang L, Takai T, Mori A, Umezu-Goto M, Ohtomo T, Ohmachi
Y, Noda Y, Hirose S, Okumura K, Ogawa H, Takada K, Hirasawa M, Hiroi T, Takaiwa

21683166 Int Immunopharmacol. 2011 Nov;11(11):1691-6. doi: 10.1016/j.intimp.2011.05.028.
Epub 2011 Jun 15.

The effect of nano-silver on the activation of nasal polyp epithelial cells by
Alternaria, Der P1 and staphylococcal enterotoxin B.

Shin SH(1), Ye MK.

22789398 J Allergy Clin Immunol. 2012 Aug;130(2):435-43.e4. doi:
1016/j.jaci.2012.05.035. Epub 2012 Jul 11.

Hypoallergenic Der p 1/Der p 2 combination vaccines for immunotherapy of house
dust mite allergy.

Chen KW(1), Blatt K, Thomas WR, Swoboda I, Valent P, Valenta R, Vrtala S.

23326313 PLoS One. 2013;8(1):e51343. doi: 10.1371/journal.pone.0051343. Epub 2013 Jan 11.

MHC class II-restricted presentation of the major house dust mite allergen Der p
1 Is GILT-dependent: implications for allergic asthma.

West LC(1), Grotzke JE, Cresswell P.

23945544 Mucosal Immunol. 2014 Mar;7(2):379-90. doi: 10.1038/mi.2013.56. Epub 2013 Aug 14.

Amelioration of ovalbumin-induced allergic airway disease following Der p 1
peptide immunotherapy is not associated with induction of IL-35.

Moldaver DM(1), Bharhani MS(1), Wattie JN(1), Ellis R(1), Neighbour H(1), Lloyd
CM(2), Inman MD(1), Larché M(1).

24844927 Cell Biol Int. 2014 Oct;38(10):1148-54. doi: 10.1002/cbin.10313. Epub 2014 Jul

Airway epithelial cell-derived insulin-like growth factor-1 triggers skewed
CD8(+) T cell polarization.

Zou JY(1), Huang SH, Li Y, Chen HG, Rong J, Ye S.

25661658 Ann Allergy Asthma Immunol. 2015 Apr;114(4):327-34. doi:
1016/j.anai.2014.12.015. Epub 2015 Feb 3.

Clinical and cytokine responses to house dust mite sublingual immunotherapy.

Potter PC(1), Baker S(2), Fenemore B(2), Nurse B(3).

29228007 PLoS One. 2017 Dec 11;12(12):e0188614. doi: 10.1371/journal.pone.0188614.
eCollection 2017.

Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood
monocyte response to Der p1.

Thomas RG(1)(2), Rivera Reyes BM(1)(2), Gaston BM(1)(2), Rivera Acosta NB(1),
Bederman IR(2), Smith LA(2), Sutton MT(2), Wang B(3), Hunt JF(4), Bonfield TL(2).

29569512 Immunotherapy. 2018 Jun;10(7):537-553. doi: 10.2217/imt-2017-0163. Epub 2018 Mar

Construction of a recombinant B-cell epitope vaccine based on a Der p1-derived
hypoallergen: a bioinformatics approach.

Fanuel S(1)(2), Tabesh S(3), Mokhtarian K(4), Saroddiny E(1), Fazlollahi MR(2),
Pourpak Z(2), Falak R(5), Kardar GA(1)(2).

30485456 Allergy. 2018 Nov 28. doi: 10.1111/all.13684. [Epub ahead of print]

Der p 1-specific regulatory T cell response during house dust mite allergen immunotherapy.

Boonpiyathad T, et al.,