| Select | PubMed ID | Description |
| 15672479 | Mol Nutr Food Res. 2004 Oct;48(5):390-9.
Isolation and characterization of natural Ara h 6: evidence for a further peanut
allergen with putative clinical relevance based on resistance to pepsin digestion
and heat.
Suhr M(1), Wicklein D, Lepp U, Becker WM.
|
| 15836759 | Clin Exp Allergy. 2005 Apr;35(4):490-7.
Purification and immunoglobulin E-binding properties of peanut allergen Ara h 6:
evidence for cross-reactivity with Ara h 2.
Koppelman SJ(1), de Jong GA, Laaper-Ertmann M, Peeters KA, Knulst AC, Hefle SL,
Knol EF.
|
| 16372900 | Biochem J. 2006 May 1;395(3):463-72.
Structure and stability of 2S albumin-type peanut allergens: implications for the
severity of peanut allergic reactions.
Lehmann K(1), Schweimer K, Reese G, Randow S, Suhr M, Becker WM, Vieths S, Rösch
P.
|
| 19438581 | Clin Exp Allergy. 2009 Jul;39(7):1099-108. doi: 10.1111/j.1365-2222.2009.03273.x.
Epub 2009 May 11.
Effector activity of peanut allergens: a critical role for Ara h 2, Ara h 6, and
their variants.
Porterfield HS(1), Murray KS, Schlichting DG, Chen X, Hansen KC, Duncan MW,
Dreskin SC.
|
| 19538351 | Clin Exp Allergy. 2009 Aug;39(8):1277-85. doi: 10.1111/j.1365-2222.2009.03294.x.
Epub 2009 Jun 15.
Capacity of purified peanut allergens to induce degranulation in a functional in
vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors.
Blanc F(1), Adel-Patient K, Drumare MF, Paty E, Wal JM, Bernard H.
|
| 21777590 | J Immunol Methods. 2011 Sep 30;372(1-2):65-70. doi: 10.1016/j.jim.2011.06.031.
Epub 2011 Jul 18.
Analysis of the effector activity of Ara h 2 and Ara h 6 by selective depletion
from a crude peanut extract.
Chen X(1), Zhuang Y, Wang Q, Moutsoglou D, Ruiz G, Yen SE, Dreskin SC.
|
| 21801247 | Clin Exp Allergy. 2011 Nov;41(11):1631-42. doi: 10.1111/j.1365-2222.2011.03830.x.
Epub 2011 Aug 1.
Effect of roasting on the allergenicity of major peanut allergens Ara h 1 and Ara
h 2/6: the necessity of degranulation assays.
Vissers YM(1), Iwan M, Adel-Patient K, Stahl Skov P, Rigby NM, Johnson PE,
Mandrup Müller P, Przybylski-Nicaise L, Schaap M, Ruinemans-Koerts J, Jansen AP,
Mills EN, Savelkoul HF, Wichers HJ.
|
| 21901150 | PLoS One. 2011;6(8):e23998. doi: 10.1371/journal.pone.0023998. Epub 2011 Aug 25.
Effect of heating and glycation on the allergenicity of 2S albumins (Ara h 2/6)
from peanut.
Vissers YM(1), Blanc F, Skov PS, Johnson PE, Rigby NM, Przybylski-Nicaise L,
Bernard H, Wal JM, Ballmer-Weber B, Zuidmeer-Jongejan L, Szépfalusi Z,
Ruinemans-Koerts J, Jansen AP, Savelkoul HF, Wichers HJ, Mackie AR, Mills CE,
Adel-Patient K.
|
| 22288514 | Clin Exp Allergy. 2012 Feb;42(2):326-36. doi: 10.1111/j.1365-2222.2011.03934.x.
The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major
elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice.
Kulis M(1), Chen X, Lew J, Wang Q, Patel OP, Zhuang Y, Murray KS, Duncan MW,
Porterfield HS, W Burks A, Dreskin SC.
|
| 22495983 | Mol Nutr Food Res. 2012 Apr;56(4):548-57. doi: 10.1002/mnfr.201100614.
Trypsin resistance of the major peanut allergen Ara h 6 and allergenicity of the
digestion products are abolished after selective disruption of disulfide bonds.
Hazebrouck S(1), Guillon B, Drumare MF, Paty E, Wal JM, Bernard H.
|
| 29542223 | Clin Exp Allergy. 2018 Jul;48(7):890-897. doi: 10.1111/cea.13134. Epub 2018 Apr
2S protein Ara h 7.0201 has unique epitopes compared to other Ara h 7 isoforms
and is comparable to 2S proteins Ara h 2 and 6 in basophil degranulation
capacity.
Hayen SM(1)(2), Ehlers AM(1)(2), den Hartog Jager CF(1), Garssen J(3)(4), Knol
EF(1)(2), Knulst AC(1)(2), Suer W(5), Willemsen LEM(3), Otten HG(2).
|
| 30414861 | J Allergy Clin Immunol. 2019 Mar;143(3):1226-1229.e10. doi:
1016/j.jaci.2018.10.039. Epub 2018 Nov 9.
Engineering of structural variants of the major peanut allergens Ara h 2 and Ara
h 6 for allergen-specific immunotherapy.
Bublin M(1), Kostadinova M(1), Radauer C(1), Varga EM(2), Hafner C(3),
Schmidthaler K(4), Saidova A(4), Maleki SJ(5), Szépfalusi Z(4), Eiwegger T(6),
Breiteneder H(1).
|
| 31108010 | Clin Exp Allergy. 2019 Aug;49(8):1107-1115. doi: 10.1111/cea.13432. Epub 2019 Jun
Variable IgE cross-reactivity between peanut 2S-albumins: The case for measuring
IgE to both Ara h 2 and Ara h 6.
Hazebrouck S(1), Guillon B(1), Paty E(2), Dreskin SC(3), Adel-Patient K(1),
Bernard H(1).
|
| 32298698 | J Allergy Clin Immunol. 2020 Sep;146(3):621-630.e5. doi:
1016/j.jaci.2020.03.026. Epub 2020 Apr 13.
Ara h 2 is the dominant peanut allergen despite similarities with Ara h 6.
Hemmings O(1), Du Toit G(2), Radulovic S(2), Lack G(3), Santos AF(4).
|
| 33434390 | Mol Nutr Food Res. 2021 Mar;65(6):e2000712. doi: 10.1002/mnfr.202000712. Epub
2021 Jan 25.
Digestion and Transport across the Intestinal Epithelium Affects the
Allergenicity of Ara h 1 and 3 but Not of Ara h 2 and 6.
Smits M(1)(2)(3), Nooijen I(4), Redegeld F(5), de Jong A(6)(4), Le TM(2)(3),
Knulst A(2)(3), Houben G(1)(2)(3), Verhoeckx K(2)(3)(4).
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