Database of 2297 Experimentally Validated Allergens

Data for Scy p 1
WHO/IUIS recognized Allergen

1  1  1  0  1  0  0  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_A_01662Allergen NameScy p 1
Source OrganismScylla paramamosain (Mud crab)KingdomAnimal
Biological Function/RoleMuscle contraction proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test  (Reference/s)Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Scy p 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Scy p 1.0101Tropomyosin
EF672351.1  (View Sequence)ABS12233.1  (View Sequence)A7L5V2  (View Sequence)
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Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome9160
AllFam-

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Scy p 1Scy p 1.0101R21, E103, E104, E115, A116, E122, E156Discontinuous/ Conformational--IgE from crab allergic patients---Dot blot33528481Residues involved in maintenance of IgE-binding
Scy p 1Scy p 1.0101AQEQLSAANTKLSequential / Linear60-71-2144611IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101ALQNAEGEVAALNRSequential / Linear77-90-2144610IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101RSEERLNTATSequential / Linear101-110-2144630IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101LAEASQAADESERSequential / Linear113-125-2144620IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101MRKVLENRSLSDEESequential / Linear126-139-2144626IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101RMDALENQLKEARFLAEEADRKYSequential / Linear140-162-2144629IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101DEVARKLAMVEADSequential / Linear163-175-2144617IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101LERAEERAESGESSequential / Linear176-188-2144622IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101KIVELEEELRVVGNNLKSLEVSSequential / Linear189-210-2144619IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101EEKANQREETYKEQIKTLANKSequential / Linear211-231-2144618IgE from crab allergic patients---Dot blot36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101I4,A10,M11,K12,L13,E14,D16,M19Discontinuous/ Conformational-2144643IgE from crab allergic patients---ELISA36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101L148,R152,L154,A158,R160,E164,V165,A166,L169,M171,V172,L176Discontinuous/ Conformational-2144644IgE from crab allergic patients---ELISA36110087UniProtKB:A0A6C0N3G5
Scy p 1Scy p 1.0101L249,E252,V253,L256,L260,V261,N262,K264,Y267,I270,L274Discontinuous/ Conformational-2144645IgE from crab allergic patients---ELISA36110087UniProtKB:A0A6C0N3G5

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Scy p 1Cra a Trp  (View AllerBase Entry)
Hal di Trp  (View AllerBase Entry)
Chla n Trp  (View AllerBase Entry)
Pat y Trp  (View AllerBase Entry)
Ven ph Trp  (View AllerBase Entry)
Sol st Trp  (View AllerBase Entry)
Lit v 1  (View AllerBase Entry)
Cra g 1  (View AllerBase Entry)
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