Database of 2233 Experimentally Validated Allergens

Data for Phl p 1
WHO/IUIS recognized Allergen

1  1  1  1  1  1  1  1  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_P_01413Allergen NamePhl p 1
Source OrganismPhleum pratense (Timothy grass)KingdomPlant
Biological Function/RoleBeta-expansinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis  (Reference/s)Mass spectrometry (MS)  (Reference/s)
Nasal Test  (Reference/s)Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test  (Reference/s)Immunochemiluminescent assay  (Reference/s)
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Phl p 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Phl p 1.0101Pollen allergen Phl pI
Z27090.1  (View Sequence)CAA81613.1  (View Sequence)Q40967  (View Sequence)
--
Phl p 1.0102Pollen allergen Phl p 1X78813.1  (View Sequence)CAA55390.1  (View Sequence)P43213  (View Sequence)
1N10 1n10  

Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome549
AllFamAF093

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Phl p 1Phl p 1.0102APYHFDLSGHAFGAMSequential / Linear124-1381N10  3912IgE from serum of grass pollen allergic patients--Immunodominant IgE haptenWestern / Immunoblot7525573-

IgE Antibody Data

Antibody data Allergen data
Antibody/ Chain Description Clone/ Isolate Antibody Source IMGT NCBI Protein (GenPept) Broad Allergen Category Allergen Id /Name Material used for Sensitization Allergic Disease Antibody studied in Reference
Single chain antibody fragment-Synthetic construct-AJI43664.1RespiratoryPhl p 1Grass pollenAllergic rhinoconjunctivitisNot specified25637023
Single chain antibody fragment-Synthetic construct-AJI43665.1RespiratoryPhl p 1Grass pollenAllergic rhinoconjunctivitisNot specified25637023
Single chain antibody fragment-Synthetic construct-AJI43666.1RespiratoryPhl p 1Grass pollenAllergic rhinoconjunctivitisNot specified25637023
Single chain antibody fragment-Synthetic constructJX169823AGH25904.1RespiratoryPhl p 1Grass pollenNot specifiedNot specified23761636
Single chain antibody fragment-Synthetic constructJX169824AGH25905.1RespiratoryPhl p 1Grass pollenNot specifiedNot specified23761636
IgE heavy chain variable regionA3-EE23Homo sapiensDQ065718ABA00128.1RespiratoryPhl p 11Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE20Homo sapiensDQ065720ABA00130.1RespiratoryPhl p 1Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE18Homo sapiensDQ065722ABA00132.1RespiratoryPhl p 1Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE13Homo sapiensDQ065725ABA00135.1RespiratoryPhl p 11Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
Single chain antibody fragmentp1-15Synthetic constructEF607094ABS72410.1RespiratoryPhl p 1Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp1-19Synthetic constructEF607095ABS72411.1RespiratoryPhl p 1Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp1-20Synthetic constructEF607096ABS72412.1RespiratoryPhl p 1Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp11-4Synthetic constructEF607125ABS72441.1RespiratoryPhl p 11Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp11-5Synthetic constructEF607126ABS72442.1RespiratoryPhl p 11Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp11-8Synthetic constructEF607127ABS72443.1RespiratoryPhl p 11Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp11-16Synthetic constructEF607128ABS72444.1RespiratoryPhl p 11Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Immunoglobulin kappa light chain variable region25Homo sapiensAJ512645CAD54751.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995
Immunoglobulin kappa light chain variable region10Homo sapiensAJ512646CAD54752.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995
Immunoglobulin kappa light chain variable region43Homo sapiensAJ512647CAD54753.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995
Immunoglobulin heavy chain variable region25Homo sapiensAJ512648CAD54754.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995
Immunoglobulin heavy chain variable region10Homo sapiensAJ512649CAD54755.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995
Immunoglobulin heavy chain variable region43Homo sapiensAJ512650CAD54756.1RespiratoryPhl p 1Grass pollenNot specifiedAdult16750995

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Phl p 1Dac g 1  (View AllerBase Entry)
Lol p 1  (View AllerBase Entry)
Poa p 1  (View AllerBase Entry)
11511525
Phl p 1Phl p 2  (View AllerBase Entry)
Phl p 5  (View AllerBase Entry)
Bet v 2  (View AllerBase Entry)
9500760