Database of 2297 Experimentally Validated Allergens

Data for Der p 23
WHO/IUIS recognized Allergen

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AllerBase IDAB_A_00719Allergen NameDer p 23
Source OrganismDermatophagoides pteronyssinus (European house dust mite)KingdomAnimal
Biological Function/RolePeritrophin-like proteinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Der p 23:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Der p 23.0101Dust mite allergen
EU414751.1  (View Sequence)ACB46292.1  (View Sequence)L7N6F8  (View Sequence)
4ZCE 4zce  

Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Der p 23 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome5747
AllFamAF077

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Der p 23Der p 23.0101K44Discontinuous/ Conformational444ZCE  -IgE from Der p 23 positive patients---Dot blot, Mutagenesis33441720Major IgE-binding residue
Der p 23Der p 23.0101E46Discontinuous/ Conformational464ZCE  -IgE from Der p 23 positive patients---Dot blot, Mutagenesis33441720Major IgE-binding residue

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data


No Cross-Reactivity Data Available