Database of 2297 Experimentally Validated Allergens

Data for Can f 1
WHO/IUIS recognized Allergen

1  1  1  1  1  0  0  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_A_00410Allergen NameCan f 1
Source OrganismCanis lupus familiaris (Dog)KingdomAnimal
Biological Function/RoleLipocalinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis  (Reference/s)Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay  (Reference/s)
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Can f 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Can f 1.0101Major allergen Can f 1
AF027177.1  (View Sequence)AAC48794.1  (View Sequence)O18873  (View Sequence)
7DRU 7dru  

Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Can f 1 with Nucleotide or Protein sequences in AllerBase:
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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Can f 1:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome174
AllFamAF015

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Can f 1Can f 1.0101H86Discontinuous/ Conformational867DRU  1642896Sera from dog-allergic patients---Mutagenesis, ELISA34699686-
Can f 1Can f 1.0101R152Discontinuous/ Conformational1527DRU  1642897Sera from dog-allergic patients---Mutagenesis, ELISA34699686-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Can f 1Can f 2   (View AllerBase Entry)17135761,18070162
Can f 1Hom s TL   (View AllerBase Entry)18070162
Can f 1Fel d 7   (View AllerBase Entry)27289080
Can f 1Fel d 1   (View AllerBase Entry)34224230