Database of 2297 Experimentally Validated Allergens

Data for Bos d 5
WHO/IUIS recognized Allergen

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AllerBase IDAB_A_00354Allergen NameBos d 5
Source OrganismBos taurus (Cattle)KingdomAnimal
Biological Function/RoleRetinol-binding proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis 
Oral Test  (Reference/s)Immunochemiluminescent assay  (Reference/s)
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay  (Reference/s)
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Bos d 5:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Bos d 5.0101Beta-lactoglobulin B
X14712.1  (View Sequence)CAA32835.1  (View Sequence)P02754  (View Sequence)
1B0O 1B8E 1BEB 
1BSO 1BSQ 1BSY 
1CJ5 1DV9 1GX8 
1GX9 1GXA 1QG5 
1UZ2 1YUP 2AKQ 
2BLG 2GJ5 2Q2M 
2Q2P 2Q39 2R56 
3BLG 3KZA 3NPO 
3NQ3 3NQ9 3PH5 
3PH6 3UEU 3UEV 
3UEW 3UEX 4DQ3 
4DQ4 4GNY 4IB6 
4IB7 4IB8 4IB9 
4IBA 4KII 4LZU 
4LZV 4Y0P 4Y0Q 
4Y0R 5IO6 6FXB 
1b0o  1b8e  1beb  
1bso  1bsq  1bsy  
1cj5  1dv9  1gx8  
1gx9  1gxa  1qg5  
1uz2  1yup  2akq  
2blg  2gj5  2q2m  
2q2p  2q39  2r56  
3blg  3kza  3npo  
3nq3  3nq9  3ph5  
3ph6  3ueu  3uev  
3uew  3uex  4dq3  
4dq4  4gny  4ib6  
4ib7  4ib8  4ib9  
4iba  4kii  4lzu  
4lzv  4y0p  4y0q  
4y0r  5io6  6fxb  

Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Bos d 5 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome164
AllFamAF015

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Bos d 5Bos d 5.0101LIVTQTMKGLDIQKVASequential / Linear17-321B8E  1BSO  1BSQ  
1BSY  1QG5  1UZ2  
2BLG  2Q2M  2Q2P  
2Q39  3BLG  3NPO  
3UEV  3UEX  4DQ4  
4IB7  4IB8  4IB9  
4IBA  4Y0P  4Y0Q  
-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101LLDAQSAPLRVYVEELKPSequential / Linear47-641B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3KZA  
3NPO  3PH5  3PH6  
3UEU  3UEV  3UEW  
3UEX  4DQ3  4DQ4  
4GNY  4IB7  4IB8  
4IB9  4IBA  4KII  
4LZU  4LZV  4Y0P  
4Y0Q  4Y0R  
-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101KPTPEGDLEILLQKSequential / Linear63-761B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3KZA  
3NPO  3PH5  3PH6  
3UEU  3UEV  3UEW  
3UEX  4DQ3  4DQ4  
4GNY  4IB7  4IB8  
4IB9  4IBA  4KII  
4LZU  4LZV  4Y0P  
4Y0Q  4Y0R  
-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101AQKKIIAEKTKISequential / Linear83-941B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3NPO  
3PH5  3PH6  3UEU  
3UEV  3UEW  3UEX  
4DQ3  4DQ4  4GNY  
4IB7  4IB8  4IB9  
4IBA  4KII  4LZU  
4LZV  4Y0P  4Y0Q  
4Y0R  
3985IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101KTKIPAVFKIDASequential / Linear91-1021B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3NPO  
3PH5  3PH6  3UEU  
3UEV  3UEW  3UEX  
4DQ3  4DQ4  4GNY  
4IB7  4IB8  4IB9  
4IBA  4KII  4LZU  
4LZV  4Y0P  4Y0Q  
4Y0R  
33732IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101EVDDEALEKFDKALKALPSequential / Linear143-1601B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3NPO  
3PH5  3PH6  3UEU  
3UEV  3UEW  3UEX  
4DQ3  4DQ4  4GNY  
4IB7  4IB8  4IB9  
4IBA  4KII  4LZU  
4LZV  4Y0P  4Y0Q  
4Y0R  
-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101KALPMHIRLSFNPTQLSequential / Linear157-1721B0O  1BEB  1BSO  
1BSQ  1BSY  1CJ5  
1DV9  1GXA  1UZ2  
1YUP  2AKQ  2BLG  
2GJ5  2Q2M  2Q39  
2R56  3BLG  3NPO  
3PH5  3PH6  3UEU  
3UEV  3UEW  3UEX  
4DQ3  4DQ4  4GNY  
4IB7  4IB8  4IB9  
4IBA  4KII  4LZU  
4LZV  4Y0P  4Y0Q  
4Y0R  
-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 5Bos d 5.0101RTPEVDDEALESequential / Linear140-1501B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3KZA  
3NPO  3PH5  3PH6  
3UEU  3UEV  3UEW  
3UEX  4DQ3  4DQ4  
4GNY  4IB7  4IB8  
4IB9  4IBA  4KII  
4LZU  4LZV  4Y0P  
4Y0Q  4Y0R  
56145IgE from serum of patients with cow's milk allergy---Radio Immuno Assay1720415-
Bos d 5Bos d 5.010134TWY36;59VEE61;K63;E71;L73;Q75;81ECAQKK86;141TPE143;169PT170;172LEEQ175;177HI178Discontinuous/ Conformational34-36;59-60;61;63;71;73;75;81-86;141-143;169-170;172-175;177-1781B0O  1B8E  1BEB  
1BSO  1BSQ  1BSY  
1CJ5  1DV9  1GXA  
1QG5  1UZ2  1YUP  
2AKQ  2BLG  2GJ5  
2Q2M  2Q2P  2Q39  
2R56  3BLG  3KZA  
3NPO  3PH5  3PH6  
3UEU  3UEV  3UEW  
3UEX  4DQ3  4DQ4  
4GNY  4IB7  4IB8  
4IB9  4IBA  4KII  
4LZU  4LZV  4Y0P  
4Y0Q  4Y0R  
151535IgE Fab Fragment from milk-allergic patientIMGT/3Dstructure-DBAgAbDb-Allergen-Antibody Complex Structure17997967-
Bos d 5Bos d 5.0102LQKWENDECAQKKIIAEKTKSequential / Linear74-93-78201IgE from serum of patients with cow's milk allergy---Microarray18774394-
Bos d 5Bos d 5.0101WENGECAQKSequential / Linear77-854LZU  -Serum from cow milk-allergic patient---Dot blot36307246-
Bos d 5Bos d 5.0101VLVLDTDYKSequential / Linear108-1164LZU  -Serum from cow milk-allergic patient---Dot blot36307246-
Bos d 5Bos d 5.0101TPEVDDEALEKSequential / Linear141-1514LZU  -Serum from cow milk-allergic patient---Dot blot36307246-
Bos d 5Bos d 5.0101TPEVDDEALEKFDKSequential / Linear141-1544LZU  -Serum from cow milk-allergic patient---Dot blot36307246-
Bos d 5Bos d 5.0101ALPMHIRSequential / Linear158-1644LZU  -Serum from cow milk-allergic patient---Dot blot36307246-

IgE Antibody Data

Antibody data Allergen data
Antibody/ Chain Description Clone/ Isolate Antibody Source IMGT NCBI Protein (GenPept) Broad Allergen Category Allergen Id /Name Material used for Sensitization Allergic Disease Antibody studied in Reference
IgE Fab light chainPDB:2R56Homo sapiens--FoodBos d 5MilkNot specifiedAdult17997967
IgE Fab heavy chainPDB:2R56Homo sapiens--FoodBos d 5MilkNot specifiedAdult17997967

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Bos d 5Ran t BLG   (View AllerBase Entry)17039668
Bos d 5Bos d 4   (View AllerBase Entry)1720415