Database of 2256 Experimentally Validated Allergens

Data for Pyr c 4
WHO/IUIS recognized Allergen

1  1  1  0  1  0  0  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_P_01580Allergen NamePyr c 4
Source OrganismPyrus communis (Pear)KingdomPlant
Biological Function/RoleActin-binding proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS) 
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray 
Radio Immunoassay  (Reference/s)
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Pyr c 4:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Pyr c 4.0101Profilin
AF129424.1  (View Sequence)AAD29410.1  (View Sequence)Q9XF38  (View Sequence)
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Sequence Analysis

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  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Pyr c 4 with Nucleotide or Protein sequences in AllerBase:
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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Pyr c 4:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome608
AllFamAF051

IgE Epitope Data

No Epitope Data Available

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Pyr c 4Api g 4  (View AllerBase Entry)
Bet v 2  (View AllerBase Entry)
Pru av 4  (View AllerBase Entry)
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