Database of 2256 Experimentally Validated Allergens

Data for Amb a 8
WHO/IUIS recognized Allergen

1  1  1  0  1  1  0  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_P_00091Allergen NameAmb a 8
Source OrganismAmbrosia artemisiifolia (Short ragweed)KingdomPlant
Biological Function/RoleActin-binding proteinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Amb a 8:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Amb a 8.0101Profilin
AY894660.1  (View Sequence)AAX77687.1  (View Sequence)Q2KN24  (View Sequence)
5EM1 5EV0 5EVE 
5em1  5ev0  5eve  
Amb a 8.0102ProfilinAY894661.1  (View Sequence)AAX77688.1  (View Sequence)Q2KN23  (View Sequence)
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Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Amb a 8 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Amb a 8:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome751
AllFamAF051

IgE Epitope Data

No Epitope Data Available

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Amb a 8Hum s PFN   (View AllerBase Entry)16174439
Amb a 8Cit la PFN   (View AllerBase Entry)21262100
Amb a 8Bet v 2  (View AllerBase Entry)
Phl p 12  (View AllerBase Entry)
Art v 4  (View AllerBase Entry)
36835455
Amb a 8Art v 4   (View AllerBase Entry)9500752