AllerBase Allergen Database

Data for Ric c 1

WHO/IUIS recognized Allergen

1 1 1 0 1 1 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_P_01601	Allergen Name	Ric c 1
Source Organism	Ricinus communis (Castor bean)	Kingdom	Plant
Biological Function/Role	Albumin	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis (Reference/s)
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST (Reference/s)
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Ric c 1:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Ric c 1.0101	2S albumin	X54158.1 (View Sequence)	CAA38097.1 (View Sequence)	P01089 (View Sequence)	1PSY	1psy

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Ric c 1 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

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Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Ric c 1: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Ric c 1	Ric c 1.0101	ESKGEREGSSSQQCR	Sequential / Linear	36-50	1PSY	-	IgE from serum of Castor bean allergic patients	-	-	-	Western / Immunoblot and mast cell degranulation assay	18262682	-
Ric c 1	Ric c 1.0101	QEVQRKDLSSCERYLRQSSS	Sequential / Linear	51-70	1PSY	-	IgE from serum of Castor bean allergic patients	-	-	-	Western / Immunoblot and mast cell degranulation assay	18262682	-
Ric c 1	Ric c 1.0101	DECQCEAIKYIAEDQQGQ	Sequential / Linear	105-123	1PSY	-	IgE from serum of Castor bean allergic patients	-	-	-	Western / Immunoblot and mast cell degranulation assay	18262682	-
Ric c 1	Ric c 1.0101	LHGEESERVAQRAGE	Sequential / Linear	125-140	1PSY	-	IgE from serum of Castor bean allergic patients	-	-	-	Western / Immunoblot and mast cell degranulation assay	18262682	-
Ric c 1	Ric c 1.0101	QEQQNLRQCQEYIKQ	Sequential / Linear	167-181	-	-	IgE from serum of Castor bean allergic patients	-	-	-	Western / Immunoblot and mast cell degranulation assay	18262682	-
Ric c 1	Ric c 1.0101	EGLRQAIEQQQSQGQ	Sequential / Linear	215-229	-	-	IgE from serum of Castor bean allergic patients	-	-	Immunodominant epitope	Western / Immunoblot and mast cell degranulation assay	18262682	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Ric c 1	Jat c 1 (View AllerBase Entry) Ric c 3 (View AllerBase Entry)	19686791