AllerBase Allergen Database

Data for Pru du 6

WHO/IUIS recognized Allergen

0 1 1 0 1 1 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_P_01560	Allergen Name	Pru du 6
Source Organism	Prunus dulcis (Almond)	Kingdom	Plant
Biological Function/Role	Legumin-like protein	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis (Reference/s)
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Pru du 6:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Pru du 6.0101	Prunin 1	GU059260.1 (View Sequence)	ADN39440.1 (View Sequence)	E3SH28 (View Sequence)	3EHK 3FZ3	3ehk 3fz3
Pru du 6.0201	Prunin 2	GU059261.1 (View Sequence)	ADN39441.1 (View Sequence)	E3SH29 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Pru du 6 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	IUIS-Allergen
Allergome	1078
AllFam	AF045

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Pru du 6	Pru du 6.0101	SSQQGRQQEQEQERQ	Sequential / Linear	118-132	-	156272	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0101	QQEQQQERQGRQQGR	Sequential / Linear	145-159	-	156426	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0101	QQEEGRQQEQQQGQQ	Sequential / Linear	161-175	-	156424	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0101	LFHVSSDHNQLDQNP	Sequential / Linear	225-239	3FZ3 3EHK	156358	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0101	QQEQQGSGNNVFSGF	Sequential / Linear	281-295	-	156425	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0101	RALPDEVLANAYQIS	Sequential / Linear	510-524	3FZ3 3EHK	156448	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	FGQNKEWQLNQLEAR	Sequential / Linear	17-31	-	156291	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	DSQPQQFQQQQQQQQ	Sequential / Linear	105-119	-	156260	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	RPSRQEGGQGQQQFQ	Sequential / Linear	121-135	-	156444	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	QNQLDQVPRRFYLAG	Sequential / Linear	185-199	-	156423	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	QQGRQQQQQQQGQQG	Sequential / Linear	209-223	-	156427	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	GNNIFSGFDTQLLAQ	Sequential / Linear	225-239	-	156317	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	RGDQERQQEEQQSQR	Sequential / Linear	281-295	-	156435	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-
Pru du 6	Pru du 6.0201	QNAFRISRQEARNLK	Sequential / Linear	465-479	-	156421	IgE from pooled serum of almond-allergic patients	-	-	-	Immunoblot(Antigen Competition)	21720172	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Pru du 6	Zea m Zein27kD (View AllerBase Entry) Zea m Zein50kD (View AllerBase Entry)	16190657