Database of 2313 Experimentally Validated Allergens
Data for Phl p 2
WHO/IUIS recognized Allergen

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Completeness Index: Denotes availibility of data for the allergen in Binary format
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0: data not available
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AllerBase IDAB_P_01417Allergen NamePhl p 2
Source OrganismPhleum pratense (Timothy grass)KingdomPlant
Biological Function/RoleGrass group 2 allergenMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test  (Reference/s)Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA)  (Reference/s)ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Phl p 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Phl p 2.0101Pollen allergen Phl p 2
X75925.1  (View Sequence)CAA53529.1  (View Sequence)P43214  (View Sequence)
1BMW 1WHO 2VXQ 
1WHP 		1bmw  1who  2vxq  
1whp  

Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Phl p 2 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome555
AllFamAF093

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Phl p 2Phl p 2.0101E56;E58;R60;H62;65DEW67;A69;N91;93RFL95;99GMKNVFDD106;P120Discontinuous/ Conformational56;58;60;62;65-67;69;91;93-95;99-106;1201BMW  1WHO  2VXQ  
1WHP  		151551IgE from serum of grass pollen allergic patientsIMGT/3Dstructure-DBAgAbDb-Allergen-Antibody Complex Structure, SPR, Competition ELISA19201867-

IgE Antibody Data

Antibody data Allergen data
Antibody/ Chain Description Clone/ Isolate Antibody Source IMGT NCBI Protein (GenPept) Broad Allergen Category Allergen Id /Name Material used for Sensitization Allergic Disease Antibody studied in Reference
IgE heavy chain variable regionA3-EQEA2Homo sapiensDQ065666ABA00076.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EQCA12Homo sapiensDQ065680ABA00090.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE79Homo sapiensDQ065686ABA00096.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE37Homo sapiensDQ065711ABA00121.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE36Homo sapiensDQ065712ABA00122.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
IgE heavy chain variable regionA3-EE30Homo sapiensDQ065714ABA00124.1RespiratoryPhl p 2Timothy grass, Cat, BirchAllergic rhinitisAdult17825890
Single chain antibody fragmentp2-2Synthetic constructEF607097ABS72413.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp2-13Synthetic constructEF607098ABS72414.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp2-18Synthetic constructEF607099ABS72415.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp2-22Synthetic constructEF607100ABS72416.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp2-29Synthetic constructEF607101ABS72417.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Single chain antibody fragmentp2-33Synthetic constructEF607102ABS72418.1RespiratoryPhl p 2Timothy grass, Mugwort, BirchAllergic rhinitisNot specified17825890
Immunoglobulin kappa chain variable region94Homo sapiensAJ458379CAD30441.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
Immunoglobulin heavy chain variable region94Homo sapiensAJ458382CAD30444.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
Immunoglobulin kappa chain variable region60Homo sapiensAJ458380CAD30442.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
Immunoglobulin heavy chain variable region60Homo sapiensAJ458383CAD30445.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
Immunoglobulin kappa chain variable region100Homo sapiensAJ458381CAD30443.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
Immunoglobulin heavy chain variable region100Homo sapiensAJ458384CAD30446.1RespiratoryPhl p 2Grass pollenNot specifiedAdult12209627
IgE-Fab light chainPDB:2VXQHomo sapiens--RespiratoryPhl p 2Grass pollenNot specifiedNot specified19201867
IgE-Fab heavy chainPDB:2VXQHomo sapiens--RespiratoryPhl p 2Grass pollenNot specifiedNot specified19201867

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Phl p 2Phl p 3   (View AllerBase Entry)16776686
Phl p 2Phl p 1  (View AllerBase Entry)
Phl p 5  (View AllerBase Entry)
Bet v 2  (View AllerBase Entry)
9500760