Database of 2313 Experimentally Validated Allergens
Data for Per a 2
WHO/IUIS recognized Allergen

0  1  1  0  1  0  1  0  0 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_A_01393Allergen NamePer a 2
Source OrganismPeriplaneta americana (American cockroach)KingdomAnimal
Biological Function/RoleAspartic proteaseMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Per a 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Per a 2.0101Per a 2 allergen
GU188391.1  (View Sequence)ADR82198.1  (View Sequence)E7BQV5  (View Sequence)
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Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Per a 2 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Per a 2:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome3037
AllFamAF004

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Per a 2Per a 2.0101DTSSYTTVIPSASCVSGGCNCANVHKYYSNSequential / Linear57-86--IgE from serum of Per a 2-allergic patients and Rabbit anti-Per a 2 antibody---ELISA25749772-
Per a 2Per a 2.0101YYRGDFTYVPLVSequential / Linear200-211-422137IgE from serum of Per a 2-allergic patients and Rabbit anti-Per a 2 antibody---ELISA25749772-
Per a 2Per a 2.0101TYHIQQNGDLCSequential / Linear299-309-422100IgE from serum of Per a 2-allergic patients and Rabbit anti-Per a 2 antibody---ELISA25749772-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data


No Cross-Reactivity Data Available