Database of 2313 Experimentally Validated Allergens

Data for Per a 1
WHO/IUIS recognized Allergen

1  1  1  0  1  0  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_A_01389Allergen NamePer a 1
Source OrganismPeriplaneta americana (American cockroach)KingdomAnimal
Biological Function/RoleCr-PII proteinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis  (Reference/s)Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Per a 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Per a 1.0101Major allergen Per a 1.0101
AF072222.1  (View Sequence)AAD13533.1  (View Sequence)Q9TZR6  (View Sequence)
--
Per a 1.0102Cr-PII proteinU78970.1  (View Sequence)AAC34312.1  (View Sequence)O18535  (View Sequence)
--
Per a 1.0103Cr-PII proteinU69957.1  (View Sequence)AAB82404.1  (View Sequence)O18530  (View Sequence)
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Per a 1.0104Cr-PII proteinU69261.1  (View Sequence)AAC34737.1  (View Sequence)O18528  (View Sequence)
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Per a 1.0201Cr-PII allergenU69260.1  (View Sequence)AAC34736.1  (View Sequence)O18527  (View Sequence)
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Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Per a 1 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Per a 1:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome530
AllFamAF127

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Per a 1Per a 1.0104LIRALFGLSequential / Linear78-85-36679IgE from serum of patients sensitive to american cockroach--Major epitopeELISA and Antigen Competition12413697-
Per a 1Per a 1.0104IRSWFGLPSequential / Linear267-274-28405IgE from serum of patients sensitive to american cockroach--Major epitopeELISA and Antigen Competition12413697-
Per a 1Per a 1.0105QDLLQNLRDKGVSequential / Linear97-108-228647rPer a 1.0105-specific monoclonal antibody---Phage Display-ELISA24991456-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Per a 1Bla g 1   (View AllerBase Entry)2262648,10329820