AllerBase Allergen Database

Data for Pen m 1

WHO/IUIS recognized Allergen

1 1 1 1 1 0 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

(Read More)

AllerBase ID	AB_A_01377	Allergen Name	Pen m 1
Source Organism	Penaeus monodon (Giant tiger prawn)	Kingdom	Animal
Biological Function/Role	Muscle contraction protein	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay (Reference/s)
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test (Reference/s)
Skin Test (Reference/s)	Microarray (Reference/s)
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Pen m 1:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Pen m 1.0101	Tropomyosin	AY827100.1 (View Sequence)	AAX37288.1 (View Sequence)	A1KYZ2 (View Sequence)	-	-
Pen m 1.0101	Tropomyosin	HM486525.1 (View Sequence)	ADM34184.1 (View Sequence)	E1A682 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Pen m 1 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

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Set E-value of your choice:
Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Pen m 1: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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*Input your Nucleotode or Protein sequence (in FASTA format) here:

Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Pen m 1	Pen m 1.0101	NRRIQLLEEDLERSEER	Sequential / Linear	89-105	-	153863	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	EASQAADESERMRK	Sequential / Linear	115-128	-	153821	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	ENRSLSDEERMD	Sequential / Linear	131-142	-	153826	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	ENQLKEARFLAEEADRKYDE	Sequential / Linear	145-164	-	153825	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	ERAEERAETGESKI	Sequential / Linear	177-190	-	153828	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	SEEKANQREEAYKEQ	Sequential / Linear	210-224	-	153886	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	ERSVQKLQKEVDRLEDE	Sequential / Linear	243-259	-	153829	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-
Pen m 1	Pen m 1.0101	EKEKYKSITDELDQTFSE	Sequential / Linear	263-280	-	153824	IgE from serum of shrimp allergic patients	-	-	Major epitope	Antigen Competition	21802470	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Pen m 1	Por p 1 (View AllerBase Entry)	23840718
Pen m 1	Aed a 10 (View AllerBase Entry) Lit v 1 (View AllerBase Entry)	DOI:10.1016/j.jaci.2013.12.378