AllerBase Allergen Database

Data for Pen c 13

WHO/IUIS recognized Allergen

1 1 1 0 1 0 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_F_01352	Allergen Name	Pen c 13
Source Organism	Penicillium citrinum ()	Kingdom	Fungi
Biological Function/Role	Serine protease	Mode of Exposure	Inhalation

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis (Reference/s)
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test (Reference/s)	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Pen c 13:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Pen c 13.0101	Alkaline serine protease	-	Q9URH1 (View Sequence)	Q9URH1 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Pen c 13 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	IUIS-Allergen
Allergome	518
AllFam	AF021

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Pen c 13	Pen c 13.0101	ANVVQSNVPSWGLARISSK	Sequential / Linear	116-134	-	164593	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	STAGEGVVFYGVDTGIDISHSD	Sequential / Linear	145-166	-	165281	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	GVDTGIDISHSDF	Sequential / Linear	155-167	-	164772	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	WGTNVVDNDNTDGNGHGTHTASTAAGSK	Sequential / Linear	173-200	-	165496	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	YGVAK	Sequential / Linear	201-205	-	165519	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	VAVKVLGADGSGTNSGVISGMDW	Sequential / Linear	210-232	-	165414	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	VLGADGSGTNSGVISGMDWAVK	Sequential / Linear	214-235	-	165449	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	AKSRGANGKYVMNMSLGGE	Sequential / Linear	237-255	-	164579	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	AAANVVKSGIFLSVAAGNE	Sequential / Linear	263-281	-	164560	IgE from serum of mold allergic patients	-	-	Immunodominant epitope	Western / Immunoblot and Antigen Competition	22506037	-
Pen c 13	Pen c 13.0101	VCTIAASTSTDGSASFTNFGSVVD	Sequential / Linear	296-319	-	165416	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	TNFGSVVDLYAPGQSITAAYPGGGSKTL	Sequential / Linear	312-339	-	165352	IgE from serum of mold allergic patients	-	-	-	Western / Immunoblot	22506037	-
Pen c 13	Pen c 13.0101	ALEGVSAGNACARIVQLATSSISRAPSGTTSK	Sequential / Linear	358-389	-	164583	IgE from serum of mold allergic patients	-	-	Immunodominant epitope	Western / Immunoblot and Antigen Competition	22506037	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Pen c 13	Asp f 13 (View AllerBase Entry) Asp fl 13 (View AllerBase Entry)	10474033
Pen c 13	Pen ch 13 (View AllerBase Entry) Asp fl 13 (View AllerBase Entry)	11893850
Pen c 13	Pen b 13 (View AllerBase Entry) Pen ch 13 (View AllerBase Entry)	8732242
Pen c 13	Asp o 13 (View AllerBase Entry)	9623506