Database of 2313 Experimentally Validated Allergens
Data for Mal d 3
WHO/IUIS recognized Allergen

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0: data not available
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AllerBase IDAB_P_01152Allergen NameMal d 3
Source OrganismMalus domestica (Apple)KingdomPlant
Biological Function/RoleLipid transfer proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Mal d 3:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Mal d 3.0101Non-specific lipid-transfer protein
AY572500.1  (View Sequence)AAT80633.1  (View Sequence)Q5J026  (View Sequence)
--
Mal d 3.0101Non-specific lipid-transfer proteinAY572501.1  (View Sequence)AAT80634.1  (View Sequence)Q5J026  (View Sequence)
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Mal d 3.0101Non-specific lipid-transfer proteinAY572502.1  (View Sequence)AAT80635.1  (View Sequence)Q5J026  (View Sequence)
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Mal d 3.0101Non-specific lipid-transfer proteinAY572503.1  (View Sequence)AAT80636.1  (View Sequence)Q5J026  (View Sequence)
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Mal d 3.0101Non-specific lipid-transfer proteinAY572504.1  (View Sequence)AAT80637.1  (View Sequence)Q5J026  (View Sequence)
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Mal d 3.0102Non-specific lipid-transfer proteinAY572516.1  (View Sequence)AAT80649.1  (View Sequence)Q5J011  (View Sequence)
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Mal d 3.0201Non-specific lipid-transfer proteinAY572517.1  (View Sequence)AAT80650.1  (View Sequence)Q5J009  (View Sequence)
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Mal d 3.0201Non-specific lipid-transfer proteinAY572520.1  (View Sequence)AAT80653.1  (View Sequence)Q5J009  (View Sequence)
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Mal d 3.0201Non-specific lipid-transfer proteinAY572521.1  (View Sequence)AAT80654.1  (View Sequence)Q5J009  (View Sequence)
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Mal d 3.0201Non-specific lipid-transfer proteinAY572522.1  (View Sequence)AAT80655.1  (View Sequence)Q5J009  (View Sequence)
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Mal d 3.0201Non-specific lipid-transfer proteinAY572523.1  (View Sequence)AAT80656.1  (View Sequence)Q5J009  (View Sequence)
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Mal d 3.0202Non-specific lipid-transfer proteinAY572530.1  (View Sequence)AAT80663.1  (View Sequence)Q5IZZ6  (View Sequence)
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Mal d 3.0202Non-specific lipid-transfer proteinAY572531.1  (View Sequence)AAT80664.1  (View Sequence)Q5IZZ6  (View Sequence)
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Mal d 3.0203Non-specific lipid-transfer proteinAY572532.1  (View Sequence)AAT80665.1  (View Sequence)Q5IZZ5  (View Sequence)
--

Sequence Analysis

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  • Pairwise alignment
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome466
AllFamAF050

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Mal d 3Mal d 3.0101YVRSGGAVPSequential / Linear40-48-23494IgE from pooled serum of patients allergic to Rosaceae fruits---Western / Immunoblot18036340-
Mal d 3Mal d 3.0101INGLARTTADRQTACNCLSequential / Linear58-75-64391IgE from pooled serum of patients allergic to Rosaceae fruits---Western / Immunoblot18036340-
Mal d 3Mal d 3.0101NNASequential / Linear88-90--IgE from pooled serum of patients allergic to Rosaceae fruits---Western / Immunoblot18036340-
Mal d 3Mal d 3.0101NVPYKISTSSequential / Linear100-108-70216IgE from pooled serum of patients allergic to Rosaceae fruits---Western / Immunoblot18036340-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Mal d 3Pru p 3   (View AllerBase Entry)10069888
Mal d 3Fra a 3  (View AllerBase Entry)
Pru p 3  (View AllerBase Entry)
16650053