AllerBase Allergen Database

Data for Jug r 4

WHO/IUIS recognized Allergen

0 1 1 0 1 0 1 0 1

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AllerBase ID	AB_P_01051	Allergen Name	Jug r 4
Source Organism	Juglans regia (English walnut)	Kingdom	Plant
Biological Function/Role	Globulin	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test (Reference/s)
Skin Test	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Jug r 4:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Jug r 4.0101	Seed storage protein	AY692446.1 (View Sequence)	AAW29810.1 (View Sequence)	Q2TPW5 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Jug r 4 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	IUIS-Allergen
Allergome	1105
AllFam	AF045

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Jug r 4	Jug r 4.0101	MAKPILLSIYLFLIV	Sequential / Linear	1-15	-	114468	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	TGVLFPGCPETFEES	Sequential / Linear	105-119	-	114627	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	VFSGFDADFLADAFN	Sequential / Linear	233-247	-	114650	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	QSENDHRRSIVRVEG	Sequential / Linear	257-271	-	114555	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	SIVRVEGRQLQVIRP	Sequential / Linear	265-279	-	114610	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	WSREEQEREERKERE	Sequential / Linear	281-295	-	114676	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	DDNGLEETICTLRLR	Sequential / Linear	313-327	-	114293	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	LTIPQNFAVVKRARN	Sequential / Linear	417-431	-	114462	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	VVKRARNEGFEWVSF	Sequential / Linear	425-439	-	114671	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	LATAFQIPREDARRL	Sequential / Linear	465-479	-	114442	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	IESWDPNNQQFQCAG	Sequential / Linear	57-71	-	114404	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	YSNAPQLVYIARGRG	Sequential / Linear	89-103	-	114695	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	RQSQQGQSREFQQDR	Sequential / Linear	121-135	-	114590	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	REFQQDRHQKIRHFR	Sequential / Linear	129-143	-	114569	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	GDIIAFPAGVAHWSY	Sequential / Linear	145-159	-	114351	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	QGQQEYEQHRRQQQR	Sequential / Linear	201-215	-	114531	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	HRRQQQRQQRPGEHG	Sequential / Linear	209-223	-	114396	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	QLQVIRPRWSREEQE	Sequential / Linear	273-287	-	114543	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	PHWNLNAHSVVYALR	Sequential / Linear	377-391	-	114508	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	SVVYALRGRAEVQVV	Sequential / Linear	385-399	-	114620	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	FNRQESTLVRSRPSR	Sequential / Linear	481-495	-	114339	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-
Jug r 4	Jug r 4.0101	VRSRPSRSRSSRSER	Sequential / Linear	489-503	-	114666	IgE from pooled serum of walnut and hazelnut allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	19631385	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Jug r 4	Coc n 11SG (View AllerBase Entry)	10359903
Jug r 4	Ses i 6 (View AllerBase Entry)	17517107
Jug r 4	Car i 4 (View AllerBase Entry)	21718052