AllerBase Allergen Database

Data for Hev b 5

WHO/IUIS recognized Allergen

1 1 1 1 1 0 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_P_00953	Allergen Name	Hev b 5
Source Organism	Hevea brasiliensis (Para rubber tree)	Kingdom	Plant
Biological Function/Role	Unknown	Mode of Exposure	Inhalation, Contact

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay (Reference/s)
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test (Reference/s)
Skin Test (Reference/s)	Microarray
	Radio Immunoassay
	RAST (Reference/s)
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Hev b 5:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Hev b 5.0101	Major latex allergen Hev b 5	U42640.1 (View Sequence)	AAC49447.1 (View Sequence)	Q39967 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Hev b 5 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	IUIS-Allergen
Allergome	389
AllFam	-

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Hev b 5	Hev b 5.0101	KNETPEVT	Sequential / Linear	15-22	-	98174	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	10359901	-
Hev b 5	Hev b 5.0101	PITEAAET	Sequential / Linear	132-139	-	78242	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	10359901	-
Hev b 5	Hev b 5.0101	TKTEEPAA	Sequential / Linear	27-34	-	78137	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	APPASEQET	Sequential / Linear	34-42	-	78104	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	EEPTAAPAEP	Sequential / Linear	50-59	-	78142	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	EKAEEVEK	Sequential / Linear	67-74	-	78141	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	IEKTEEPA	Sequential / Linear	75-82	-	78143	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	DQTTPEEKPAEPE	Sequential / Linear	86-98	-	78255	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	EEPKHETK	Sequential / Linear	103-111	-	78136	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	EKPAEEEKP	Sequential / Linear	124-132	-	78145	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-
Hev b 5	Hev b 5.0101	TEVPVEKT	Sequential / Linear	142-149	-	78276	IgE from serum of latex allergic subjects	-	-	-	Western / Immunoblot	11398087	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Hev b 5	Man e 5 (View AllerBase Entry)	23526605
Hev b 5	Pru ar 5 (View AllerBase Entry)	31254775