Database of 2313 Experimentally Validated Allergens
Data for Hev b 3
WHO/IUIS recognized Allergen

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0: data not available
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AllerBase IDAB_P_00951Allergen NameHev b 3
Source OrganismHevea brasiliensis (Para rubber tree)KingdomPlant
Biological Function/RoleSmall rubber particle proteinMode of ExposureInhalation, Contact

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Hev b 3:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Hev b 3.0101Small rubber particle protein
AF051317.1  (View Sequence)AAC82355.1  (View Sequence)O82803  (View Sequence)
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Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome387
AllFamAF125

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Hev b 3Hev b 3.0101AEEVEEERLKSequential / Linear2-11-893IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101ERLKYLDFVRSequential / Linear8-17-14028IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101TLYLYAKDISSequential / Linear29-38-65160IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101LKPGVDTIENSequential / Linear41-50-36988IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101YYIPLEAVKFVSequential / Linear60-70-76523IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot and Antigen Competition11275264-
Hev b 3Hev b 3.0101VPPVIKQVSASequential / Linear85-94-70439IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101APRIVLDVASSequential / Linear103-112-3780IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101GVQEGAKALYSequential / Linear118-127-23107IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101AVITWRALNKSequential / Linear138-147-5391IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101VPTAVYFSEKSequential / Linear159-168-70490IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 3Hev b 3.0101QGYRVSSYLPSequential / Linear179-188-50990IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Hev b 3Hev b 1   (View AllerBase Entry)11275264