Database of 2313 Experimentally Validated Allergens
Data for Hev b 2
WHO/IUIS recognized Allergen

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AllerBase IDAB_P_00950Allergen NameHev b 2
Source OrganismHevea brasiliensis (Para rubber tree)KingdomPlant
Biological Function/RoleGlucanaseMode of ExposureInhalation, Contact

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Hev b 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Hev b 2.0101Glucan endo-1,3-beta-glucosidase
U22147.1  (View Sequence)AAA87456.1  (View Sequence)P52407  (View Sequence)
4HPG 4IIS 4hpg  4iis  

Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Hev b 2 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome386
AllFamAF063

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Hev b 2Hev b 2.0101VSEVIALYKKSNITRMRIYDPNRASequential / Linear52-754HPG  4IIS  111923IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101TNPSNAKSWVQKNVRGFWSSVLFRSequential / Linear100-123-111839IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101AWLAQFVLPSequential / Linear139-1474HPG  4IIS  111135IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101DQIKVSTAIDLTSequential / Linear163-1744HPG  4IIS  111212IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101DPIIGFLSSIRSPLLSequential / Linear196-2104HPG  4IIS  111209IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101WDGQRGYKNLFDATLDALSequential / Linear241-2584HPG  4IIS  111945IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101NLIQHVKGGTPKRPNSequential / Linear298-312-111588IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101GLFFPDKRPKYNLNFSequential / Linear337-351-111347IgE from serum of latex allergic patients---Western / Immunoblot19185347-
Hev b 2Hev b 2.0101TEHNATILFLKSDMSequential / Linear361-374-111822IgE from serum of latex allergic patients---Western / Immunoblot19185347-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Hev b 2Cap a Gluc  (View AllerBase Entry)
Cap a 30kD  (View AllerBase Entry)
15544599
Hev b 2Mus a 5   (View AllerBase Entry)19185347