Database of 2313 Experimentally Validated Allergens
Data for Hev b 1
WHO/IUIS recognized Allergen

1  1  1  1  1  0  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_P_00943Allergen NameHev b 1
Source OrganismHevea brasiliensis (Para rubber tree)KingdomPlant
Biological Function/RoleRubber elongation factorMode of ExposureInhalation, Contact

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Hev b 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Hev b 1.0101Rubber elongation factor protein
X56535.1  (View Sequence)CAA39880.1  (View Sequence)P15252  (View Sequence)
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Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome379
AllFamAF125

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Hev b 1Hev b 1.0101AEDEDNQQGQSequential / Linear2-11-849IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101KYLGFVQDAASequential / Linear16-25-34502IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot and Antigen Competition11275264-
Hev b 1Hev b 1.0101YLFAKDKSGPSequential / Linear36-45-74645IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101LQPGVDIIEGSequential / Linear46-55-38948IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot and Antigen Competition11275264-
Hev b 1Hev b 1.0101AVPLYNRFSYSequential / Linear61-70-5502IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101YNRFSYIPNGSequential / Linear65-74-75209IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101IDRSLPPIVKSequential / Linear90-99-25664IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101KDASIQVVSASequential / Linear99-108-30115IgE from serum of latex allergic patients with spina bifida--Immunodominant epitopeWestern / Immunoblot11275264-
Hev b 1Hev b 1.0101FSNVYLFAKDKSGPLQPGVSequential / Linear32-50-17795IgE from serum of latex allergic patients---ELISA8732237-
Hev b 1Hev b 1.0101QPGVDIIEGPVKNVAVPLYSequential / Linear47-65-51847IgE from serum of latex allergic patients---ELISA and Antigen Competition8732237-
Hev b 1Hev b 1.0101SLPGQTKILAKVFYGENSequential / Linear122-138-59387IgE from serum of latex allergic patients---ELISA and Antigen Competition8732237-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Hev b 1Hev b 3   (View AllerBase Entry)11275264
Hev b 1Car p PPI   (View AllerBase Entry)8588696