Database of 2313 Experimentally Validated Allergens
Data for Gly m 5
WHO/IUIS recognized Allergen

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AllerBase IDAB_P_00904Allergen NameGly m 5
Source OrganismGlycine max (Soybean)KingdomPlant
Biological Function/RoleVicilinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA)  (Reference/s)ImmunoCAP Test  (Reference/s)
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Gly m 5:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Gly m 5.0101Alpha subunit of beta conglycinin
AB008678.2  (View Sequence)BAA23360.2  (View Sequence)O22120  (View Sequence)
--
Gly m 5.0201Alpha' subunit of beta-conglycininAB008680.2  (View Sequence)BAA74452.2  (View Sequence)Q9FZP9  (View Sequence)
1UIK 1uik  
Gly m 5.0301Beta-conglycinin, beta chainS44893.1  (View Sequence)AAB23463.1  (View Sequence)P25974  (View Sequence)
1UIJ 1IPJ 1IPK 
1uij  1ipj  1ipk  
Gly m 5.0302Beta-conglycinin, beta chain--P25974  (View Sequence)
1IPK 1ipk  

Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome5816
AllFamAF045

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Gly m 5Gly m 5.0101ECEEGEIPRPRPRPQHPEREPQQPGEKEESequential / Linear5-33-181299IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101HEQREEQEWPRKEEKRGEKGSEEEDESequential / Linear55-80-181334IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101QFPFPRPPHQKEERKQEEDEDEEQQRSequential / Linear90-115-181432IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101DEEQQRESEESEDSELRRHKNKNPFLSequential / Linear110-135-181288IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101NKNPFLFGSNRFETLFKNQYGRIRVLQRFSequential / Linear130-158-181406IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101TAILSLVNNDDRDSYRLQSGDALRVPSGTSequential / Linear200-229-181474IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101YYVVNPDNNENLRLITLAIPVNKPGRFESSequential / Linear230-260-181524IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101EQIRALSKRAKSSSRKTISSEDKPFNSequential / Linear320-345-181307IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101SEDKPFNLRSRDPIYSNKLGKFFEITPEKNSequential / Linear338-368-181455IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101DPIYSNKLGKFFEITPEKNPQLRDLDSequential / Linear350-375-181292IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101QRESYFVDAQPKKKEEGNKGRKGPLSSILRSequential / Linear510-540-181434IgE from serum of soybean allergic patients--Major epitopeDot-blot inhibition assay23454299-
Gly m 5Gly m 5.0101LRRHKNKNPFLFGSNRFESequential / Linear125-142--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Bos d 9 cross-reactive epitope
Gly m 5Gly m 5.0101KNPQLRDLDIFLSIVDMNESequential / Linear367-385--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Bos d 9 cross-reactive epitope
Gly m 5Gly m 5.0101GNKGRKGPLSSILRAFYSequential / Linear527-543--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Bos d 9 cross-reactive epitope
Gly m 5Gly m 5.0301GRIRLLQRFNKRSPQLENLRDYRSequential / Linear51-731UIJ  1IPJ  1IPK  
-Sera from soybean allergic patients---ELISA32198043Also an IgG-binding epitope
Gly m 5Gly m 5.0301LSRRAKSSSRKTISSEDEPFNLRSRNPIYSSequential / Linear221-2501UIJ  1IPJ  1IPK  
-Sera from soybean allergic patients---ELISA32198043Also an IgG-binding epitope
Gly m 5Gly m 5.0101QLQNLRDYRILEFNSKPNTSequential / Linear164-182-1387227Sera from infants allergic to Cow Milk or mice mAbs---Western / Immunoblot32896409Bos d 9 IgE and IgG cross-reactive epitope
Gly m 5Gly m 5.0101KEQIRALSKRAKSSSRKTISSEDSequential / Linear319-341-1383331Sera from infants allergic to Cow Milk or mice mAbs---Western / Immunoblot32896409Bos d 9 IgE and IgG cross-reactive epitope

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Gly m 5Bos d 8   (View AllerBase Entry)24416141
Gly m 5Bos d 9   (View AllerBase Entry)28643898