Database of 2313 Experimentally Validated Allergens
Data for Gal d 4
WHO/IUIS recognized Allergen

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Completeness Index: Denotes availibility of data for the allergen in Binary format
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0: data not available
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AllerBase IDAB_A_00872Allergen NameGal d 4
Source OrganismGallus domesticus (Chicken)KingdomAnimal
Biological Function/RoleGlycosidase, HydrolaseMode of ExposureIngestion, Inhalation, Contact

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay  (Reference/s)
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Gal d 4:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Gal d 4.0101Lysozyme C
V00428.1  (View Sequence)CAA23711.1  (View Sequence)P00698  (View Sequence)
1NDG 193L 1AKI 
1AT5 1BGI 1BWJ 
1FLY 1IOR 1IR7 
1J1O 1JA2 1JA6 
1JA7 1JIS 1JPO 
1KIP 1KXW 2BLX 
2DQC 2D91 2FBB 
2ZYP 3A8Z 3IJV 
3E3D 3WUL 3ZEK 
4A7D 4A8A 4AGA 
4AXT 4B49 4BAD 
4DC4 4XJB 4XYY 
5AMY 5B05 5B06 
5B07 5C6I 5DLA 
5KKI 5KY1 5LYM 
5LYT 5LYZ 5NBJ 
6LYZ 7LYZ 8LYZ 
9LYZ 		1ndg  193l  1aki  
1at5  1bgi  1bwj  
1fly  1ior  1ir7  
1j1o  1ja2  1ja6  
1ja7  1jis  1jpo  
1kip  1kxw  2blx  
2dqc  2d91  2fbb  
2zyp  3a8z  3ijv  
3e3d  3wul  3zek  
4a7d  4a8a  4aga  
4axt  4b49  4bad  
4dc4  4xjb  4xyy  
5amy  5b05  5b06  
5b07  5c6i  5dla  
5kki  5ky1  5lym  
5lyt  5lyz  5nbj  
6lyz  7lyz  8lyz  
9lyz  

Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Gal d 4 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Gal d 4:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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    *Input your Nucleotode or Protein sequence (in FASTA format) here:

        


Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome362
AllFamAF016

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Gal d 4Gal d 4.010132RHG34;37NYR39;80WW81;90SRNL93;N95;T107;N111;114KKI116;118SDG120Discontinuous/ Conformational32-34;37-39;80-81;90-93;95;107;111;114-116;118-1201NDG  193L  1AKI  
1AT5  1BGI  1IOR  
1JA2  1JIS  1KIP  
2BLX  3WUL  3ZEK  
4A8A  4BAD  5DLA  
5LYM  5LYZ  9LYZ  
146698Anti-Lysozyme Antibody HyHEL-8IMGT/3Dstructure-DBAgAbDb-Allergen-Antibody Complex Structure, SPR12740607-
Gal d 4Gal d 4.0101FGRCELAAAMKSequential / Linear21-311NDG  2218334Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101DNYRGSequential / Linear36-401NDG  2218325Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101CAAKFSequential / Linear48-521NDG  2218316Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101WCNDGRTPGSRSequential / Linear81-911NDG  2218437Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101LCNIPSequential / Linear93-971NDG  2218366Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101LSSDITASSequential / Linear102-1091NDG  2218377Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101CKGSequential / Linear133-1351NDG  2218320Chinese egg-allergic sera---Dot blot37053565-
Gal d 4Gal d 4.0101SLGNWVCAAKFSequential / Linear42-521NDG  2218413Chinese egg-allergic sera--Immunodominant epitopeDot blot37053565-
Gal d 4Gal d 4.0101SALLSSDITASSequential / Linear99-1091NDG  2218409Chinese egg-allergic sera--Immunodominant epitopeDot blot37053565-
Gal d 4Gal d 4.0101GNGMNAWVAWRSequential / Linear120-1301NDG  2218347Chinese egg-allergic sera--Immunodominant epitopeDot blot37053565-

IgE Antibody Data

Antibody data Allergen data
Antibody/ Chain Description Clone/ Isolate Antibody Source IMGT NCBI Protein (GenPept) Broad Allergen Category Allergen Id /Name Material used for Sensitization Allergic Disease Antibody studied in Reference
Immunoglobulin kappa light chain-Mus musculusV00807CAA24189.1Respiratory, Food, ContactGal d 4Hen egg white LysozymeNot specifiedNot specified12740607
Immunoglobulin gamma 2a-chain-Mus musculusM35032AAA37919.1Respiratory, Food, ContactGal d 4Hen egg white LysozymeNot specifiedNot specified12740607

Cross-reactivity Data


No Cross-Reactivity Data Available