AllerBase Allergen Database

Data for Fag e 1

0 1 1 0 1 0 1 0 0

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AllerBase ID	AB_P_00787	Allergen Name	Fag e 1
Source Organism	Fagopyrum esculentum (Common buckwheat)	Kingdom	Plant
Biological Function/Role	Globulin	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis (Reference/s)
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test (Reference/s)
Skin Test	Microarray (Reference/s)
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Fag e 1:

Not Available

Allergen	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Fag e 1	13S globulin	D87980.1, AB828119.1 (View Sequence)	BAA21758.1, BAO50870.1 (View Sequence)	O23878 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Fag e 1 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	-
Allergome	698
AllFam	AF045

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Fag e 1	-	QNVNRPSR	Sequential / Linear	360-367	-	16452	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	NNLPILEF	Sequential / Linear	384-391	-	10192	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	WNLNAH	Sequential / Linear	411-416	-	21776	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	EGRSVF	Sequential / Linear	434-439	-	18963	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	KAGNEG	Sequential / Linear	460-465	-	5604	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	IAGKTSVLRA	Sequential / Linear	482-491	-	25291	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	KEAFRL	Sequential / Linear	506-511	-	8789	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	SRDEKERERF	Sequential / Linear	526-535	-	60632	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	15310064	-
Fag e 1	-	SSTMRARQCRLDQLTSSQ	Sequential / Linear	23-40	-	111804	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	KIRSEGGTIEVWDEE	Sequential / Linear	44-58	-	111455	IgE from serum of buckwheat allergic patients	-	-	Minor epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	MRVTVQPDSLSLPSYYSSPRLV	Sequential / Linear	70-91	-	111571	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	DAHQPTRRVRKGDVVALP	Sequential / Linear	136-153	-	111186	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	QGGSKEGKSQKLNS	Sequential / Linear	197-210	-	111669	IgE from serum of buckwheat allergic patients	-	-	Minor epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	ESDERGPIVKARKNMRQMVT	Sequential / Linear	238-257	-	111260	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	NMRFRHNLGPRTEADIASRQAGRIHSVD	Sequential / Linear	278-306	-	111592	IgE from serum of buckwheat allergic patients	-	-	Minor epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	NAMLAPAWPLSGHRVFYVLRGEAQRQI	Sequential / Linear	328-354	-	111576	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	PQFYISTCRAGRD	Sequential / Linear	376-388	-	111640	IgE from serum of buckwheat allergic patients	-	-	Minor epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	HASVFKGMPIPVLSNSYQISPR	Sequential / Linear	409-430	-	111393	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1
Fag e 1	-	QTRSHEHGLFSPFGGRS	Sequential / Linear	447-453	-	111692	IgE from serum of buckwheat allergic patients	-	-	Major epitope	Western / Immunoblot	19463732	GenBank Protein: BAO50870.1

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

No Cross-Reactivity Data Available