AllerBase Allergen Database

Data for Der f 4

WHO/IUIS recognized Allergen

0 1 1 0 1 0 1 0 0

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

(Read More)

AllerBase ID	AB_A_00698	Allergen Name	Der f 4
Source Organism	Dermatophagoides farinae (American house dust mite)	Kingdom	Animal
Biological Function/Role	Amylase	Mode of Exposure	Inhalation

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray (Reference/s)
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Der f 4:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Der f 4.0101	Alpha-amylase	KJ400030.1 (View Sequence)	AHX03180.1 (View Sequence)	A0A023NMA7 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Der f 4 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

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Set E-value of your choice:
Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Der f 4: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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*Input your Nucleotode or Protein sequence (in FASTA format) here:

Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Der f 4	Der f 4.0101	DIHTRSGDEQQFRR	Sequential / Linear	92-105	-	558037	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-
Der f 4	Der f 4.0101	QSGLGTNGHH	Sequential / Linear	130-139	-	558167	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-
Der f 4	Der f 4.0101	SHPFIYHE	Sequential / Linear	248-255	-	558180	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-
Der f 4	Der f 4.0101	ITNVFRNN	Sequential / Linear	284-291	-	558094	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-
Der f 4	Der f 4.0101	VGPPTDQHGNI	Sequential / Linear	378-388	-	558201	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-
Der f 4	Der f 4.0101	VGHDEFDAFVAYHI	Sequential / Linear	506-519	-	558200	Pooled sera from pediatric patients with D. farinae hypersensitivity	-	-	-	Microarray	27481284	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

No Cross-Reactivity Data Available