Database of 2313 Experimentally Validated Allergens
Data for Der f 21
WHO/IUIS recognized Allergen

1  1  1  0  1  1  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
(Read More)


Download data as Text file

AllerBase IDAB_A_00682Allergen NameDer f 21
Source OrganismDermatophagoides farinae (American house dust mite)KingdomAnimal
Biological Function/RoleMite group-21 allergenMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test  (Reference/s)Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Der f 21:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Der f 21.0101Allergen Der f 21
KF732965.1  (View Sequence)AHC94806.1  (View Sequence)B2GM84  (View Sequence)
5YNX 5YNY 5ynx  5yny  

Sequence Analysis

  • BLAST
  • Pairwise alignment
  • Hide Tab

  • BLAST Nucleotide/Protein sequence of Allergen Der f 21 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

    OR
    Set E-value of your choice:    

       

  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Der f 21:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

    *

    *Input your Nucleotode or Protein sequence (in FASTA format) here:

        


Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome5843
AllFamAF156

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Der f 21Der f 21.0101K27;K43;K59-E60;K63;K65Discontinuous/ Conformational27;43;59-60;63;655YNX  5YNY  886587IgE from serum from patients atopic to D. farinae extract, rDer f 21---Site-directed mutagenesis with dot-blot assay30894561-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Der f 21Der f 5  (View AllerBase Entry)
Blo t 5  (View AllerBase Entry)
26238285
Der f 21Tyr p 5  (View AllerBase Entry)
Tyr p 21  (View AllerBase Entry)
Blo t 5  (View AllerBase Entry)
Blo t 21  (View AllerBase Entry)
26238285
Der f 21Der f 5   (View AllerBase Entry)27069539