Database of 2313 Experimentally Validated Allergens
Data for Der f 2
WHO/IUIS recognized Allergen

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AllerBase IDAB_A_00680Allergen NameDer f 2
Source OrganismDermatophagoides farinae (American house dust mite)KingdomAnimal
Biological Function/RoleNPC2 family proteinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test  (Reference/s)Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay  (Reference/s)
Passive Cutaneous Anaphylaxis (PCA)  (Reference/s)ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay  (Reference/s)
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Der f 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Der f 2.0101Mite group 2 allergen Der f 2
D10447.1  (View Sequence)BAA01239.1  (View Sequence)Q00855  (View Sequence)
1AHK 1AHM 2F08 
1WRF 		1ahk  1ahm  2f08  
1wrf  
Der f 2.0102Mite group 2 allergen Der f 2D10448.1  (View Sequence)BAA01240.1  (View Sequence)Q00855  (View Sequence)
--
Der f 2.0103Mite group 2 allergen Der f 2D10449.1  (View Sequence)BAA01241.1  (View Sequence)Q00855  (View Sequence)
1XWV 1xwv  
Der f 2.0104Mite group 2 allergen Der f 2-----
Der f 2.0105Major Der f 2 isoformAY066008.1  (View Sequence)AAL47677.1  (View Sequence)Q8WQK5  (View Sequence)
--
Der f 2.0106Mite allergen Der f 2AJ862836.1  (View Sequence)CAI05848.1  (View Sequence)Q5TIW2  (View Sequence)
--
Der f 2.0107Der f 2AJ862837.1  (View Sequence)CAI05849.1  (View Sequence)Q5TIW1  (View Sequence)
--
Der f 2.0108Mite allergen Der f 2AJ862838.1  (View Sequence)CAI05850.1  (View Sequence)Q5TIW0  (View Sequence)
--
Der f 2.0109Der f 2 allergenDQ185511.1  (View Sequence)ABA39438.1  (View Sequence)Q3HWZ2  (View Sequence)
--
Der f 2.0110Der f 2 allergen-----
Der f 2.0111Der f 2 allergen-----
Der f 2.0112Der f 2 allergenAY283288.1  (View Sequence)AAP35073.1  (View Sequence)A1KXH0  (View Sequence)
--
Der f 2.0113Der f 2 allergen-----
Der f 2.0114Der f 2 allergen-----
Der f 2.0115Der f 2 allergen-----
Der f 2.0116Der f 2 allergenEF205129.1  (View Sequence)ABN14313.1  (View Sequence)A3F5F1  (View Sequence)
--
Der f 2.0117Der f 2 allergen-----

Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome302
AllFamAF111

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Der f 2-KVMVDGCHSequential / Linear32-391AHK  1AHM  1XWV  
2F08  1WRF  		558105Pooled sera from pediatric patients with D. farinae hypersensitivity---Microarray27481284GenBank: FJ436110.1
Der f 2-LVKGQQYDIKSequential / Linear97-1061AHK  1AHM  2F08  
1WRF  		558110Pooled sera from pediatric patients with D. farinae hypersensitivity---Microarray27481284GenBank: FJ436110.1
Der f 2-VTVKLIGDSequential / Linear123-1301AHK  1AHM  2F08  
1WRF  		558207Pooled sera from pediatric patients with D. farinae hypersensitivity---Microarray27481284GenBank: FJ436110.1
Der f 2Der f 2.0101DQVDVKDCANNEIKKVMVDGCHGSDPCIISequential / Linear18-461AHK  1AHM  9918IgE from serum of mite sensitive atopic patients---Western / Immunoblot and Antigen Competition9224967-
Der f 2Der f 2.0101IATSequential / Linear138-1401AHK  1AHM  1XWV  
2F08  1WRF  		96373IgE from serum of mite sensitive atopic patients---Western / Immunoblot and Antigen Competition9224967-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Der f 2Der p 2  (View AllerBase Entry)
Eur m 2  (View AllerBase Entry)
12372994
Der f 2Der f 35  (View AllerBase Entry)
Pso o 2  (View AllerBase Entry)
28439905
Der f 2Der f 22   (View AllerBase Entry)30082894