AllerBase Allergen Database

Data for Cry j 2

WHO/IUIS recognized Allergen

1 1 1 1 1 0 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_P_00580	Allergen Name	Cry j 2
Source Organism	Cryptomeria japonica (Japanese cedar)	Kingdom	Plant
Biological Function/Role	Polygalacturonase	Mode of Exposure	Inhalation

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay (Reference/s)
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test (Reference/s)	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST (Reference/s)
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Cry j 2:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Cry j 2.0101	Polygalacturonase	D29772.1 (View Sequence)	BAA06172.1 (View Sequence)	P43212 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Cry j 2 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

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Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Cry j 2: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Cry j 2	Cry j 2.0101	KWVNGREI	Sequential / Linear	169-176	-	34335	IgE from serum of patients with CJ pollinosis	-	-	Major epitope	ELISA and Antigen Competition	12580914	-
Cry j 2	Cry j 2.0101	GRENSRAEVSYVHVNGAKFI	Sequential / Linear	285-305	-	22022	IgE from serum of patients with CJ pollinosis	-	-	-	Inhibition ELISA	23504147	-
Cry j 2	Cry j 2.0101	TYKNIRGTSATAAAIQLKCS	Sequential / Linear	366-385	-	188551	IgE from serum of patients with CJ pollinosis	-	-	-	Inhibition ELISA	23504147	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Cry j 2	Cha o 2 (View AllerBase Entry)	26916996