AllerBase Allergen Database

Data for Cra a Trp

1 1 1 0 1 0 1 0 1

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

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AllerBase ID	AB_A_02296	Allergen Name	Cra a Trp
Source Organism	Crassostrea angulata (Pacific oyster)	Kingdom	Animal
Biological Function/Role	Muscle contraction protein	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Cra a Trp:

Not Available

Allergen	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Cra a Trp	Tropomyosin	KY549366 (View Sequence)	ARX70262 (View Sequence)	A0A1Z1VMW2 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Cra a Trp with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

OR
Set E-value of your choice:
Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Cra a Trp: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

*

*Input your Nucleotode or Protein sequence (in FASTA format) here:

Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Cra a Trp	-	KENAQDR	Sequential / Linear	15-21	-	2116381	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	QQLRDTEEQKAKIEE	Sequential / Linear	27-41	-	2116399	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	LTSLQKKHS	Sequential / Linear	43-51	-	2116383	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	NEKYQECQTKMEEAEK	Sequential / Linear	61-76	-	2116386	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	EIQSLNR	Sequential / Linear	84-90	-	2116376	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	AARKLAITEV	Sequential / Linear	165-174	-	2116370	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	RLEAAEAKVYE	Sequential / Linear	182-192	-	2116400	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	QLSVVANNIKTL	Sequential / Linear	196-207	-	2116398	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	SQREDSYEET	Sequential / Linear	215-224	-	2116402	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-
Cra a Trp	-	LAEKERYK	Sequential / Linear	261-268	-	2116382	IgE from Oyster-sensitive patients	-	-	-	Dot blot,ELISA	35848932	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Cra a Trp	Cra g 1 (View AllerBase Entry) Hal di Trp (View AllerBase Entry) Chla n Trp (View AllerBase Entry) Pat y Trp (View AllerBase Entry) Ven ph Trp (View AllerBase Entry) Sol st Trp (View AllerBase Entry) Lit v 1 (View AllerBase Entry) Scy p 1 (View AllerBase Entry)	35848932