AllerBase Allergen Database

Data for Cra a 4

WHO/IUIS recognized Allergen

1 1 1 0 1 0 1 0 0

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

(Read More)

AllerBase ID	AB_A_02136	Allergen Name	Cra a 4
Source Organism	Crassostrea angulata (Pacific oyster)	Kingdom	Animal
Biological Function/Role	Calcium-binding protein	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test (Reference/s)	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Cra a 4:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Cra a 4.0101	Sarcoplasmic calcium-binding protein	MN956521 (View Sequence)	QIJ32297 (View Sequence)	A0A6G7MAZ4 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Cra a 4 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

OR
Set E-value of your choice:
Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Cra a 4: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

*

*Input your Nucleotode or Protein sequence (in FASTA format) here:

Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Cra a 4	Cra a 4.0101	KISIEDVEESRN	Sequential / Linear	22-33	-	1558351	Sera from Oyster-allergic patients	-	-	-	ELISA	34338271	-
Cra a 4	Cra a 4.0101	TGAGKEISESEF	Sequential / Linear	64-75	-	1560554	Sera from Oyster-allergic patients	-	-	-	ELISA	34338271	-
Cra a 4	Cra a 4.0101	TEAYKKDKVGF	Sequential / Linear	80-90	-	1560537	Sera from Oyster-allergic patients	-	-	-	ELISA	34338271	-
Cra a 4	Cra a 4.0101	TNKDRTIDED	Sequential / Linear	107-116	-	1560631	Sera from Oyster-allergic patients	-	-	-	ELISA	34338271	-
Cra a 4	Cra a 4.0101	NKHVPLKDIVSEWVKF	Sequential / Linear	144-159	-	1559312	Sera from Oyster-allergic patients	-	-	-	ELISA	34338271	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

No Cross-Reactivity Data Available