Database of 2313 Experimentally Validated Allergens
Data for Cra a 2
WHO/IUIS recognized Allergen

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Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_A_02243Allergen NameCra a 2
Source OrganismCrassostrea angulata (Pacific oyster)KingdomAnimal
Biological Function/RoleKinaseMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Cra a 2:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Cra a 2.0101Arginine kinase
MW864167  (View Sequence)QZP44316  (View Sequence)---

Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Cra a 2 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

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  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Cra a 2:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome-
AllFam-

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Cra a 2Cra a 2.0101SGAGVYACDPEGYEVFKESequential / Linear56-73-1641094IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101PVIMDYHKVDKVEHPPSequential / Linear77-92-1640420IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101CDFGPQDKLGFDPLDSequential / Linear93-107-1636526IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101GRSHEGYPFPPVSSequential / Linear121-133-1637924IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101TDEQRKEMENKTISequential / Linear134-146-1641532IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101TMTPEENQQLIDSequential / Linear165-176-1641742IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101DKMLGDAGGYNGWPKASequential / Linear185-200-1636755IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101QKGGDVGEVYKRSequential / Linear227-238-1640530IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101GEHTESVGGVYDISNKRRSequential / Linear306-323-1637670IgE from sera of Oyster-sensitive patients---Dot blot, ELISA34664604-
Cra a 2Cra a 2.0101PLDATGEFIVSTRVSequential / Linear105-118-2145105IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-
Cra a 2Cra a 2.0101YKRLVSAIKQLESequential / Linear236-247-2145266IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-
Cra a 2Cra a 2.0101S2,D3,L4,P5,L7,W8,K9,K10,S13,S16,K21,K33,A44,D45,L52,L54,D190Discontinuous/ Conformational--IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-
Cra a 2Cra a 2.0101R48,N53,P130,P131,N183,M187,G192,N195,W197,N216,C264,H308Discontinuous/ Conformational--IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-
Cra a 2Cra a 2.0101D107,I113,V114,S115,R117,D177,M226,Q227,R302,I304,S311,V312,V315Discontinuous/ Conformational--IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-
Cra a 2Cra a 2.0101D107,F112,I113,V114,S115,D177,H178,G229,H277,I304,H305,G306,S311,V312,G313,G314,V315Discontinuous/ Conformational--IgE from sera of Oyster-allergic patients---Dot blot,iELISA36205062-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Cra a 2Scy p 2  (View AllerBase Entry)
Lit v 2  (View AllerBase Entry)
34664604