AllerBase Allergen Database

Data for Car i 4

WHO/IUIS recognized Allergen

0 1 1 0 1 0 1 0 1

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AllerBase ID	AB_P_00451	Allergen Name	Car i 4
Source Organism	Carya illinoinensis (Pecan)	Kingdom	Plant
Biological Function/Role	Legumin	Mode of Exposure	Ingestion

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography	Lymphocyte proliferation assay
Bronchial Test	ELISA	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis (Reference/s)
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test	Microarray
	Radio Immunoassay
	RAST
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Car i 4:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Car i 4.0101	11S legumin protein	EU113051.1 (View Sequence)	ABW86978.1 (View Sequence)	B5KVH4 (View Sequence)	-	-

Sequence Analysis

BLAST
Pairwise alignment
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BLAST Nucleotide/Protein sequence of Allergen Car i 4 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUIS	IUIS-Allergen
Allergome	8299
AllFam	AF045

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Car i 4	Car i 4.0101	PHYSNAPQLVYI	Sequential / Linear	88-99	-	157741	IgE from pooled serum of Pecan allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	EESQRQSQQGQR	Sequential / Linear	118-129	-	157186	IgE from pooled serum of Pecan allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	QRQSQQGQRREF	Sequential / Linear	121-132	-	157812	IgE from pooled serum of Pecan allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	REFQQDRHQKIR	Sequential / Linear	130-141	-	157835	IgE from pooled serum of Pecan allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	QGQQEYEQHRRQ	Sequential / Linear	202-213	-	157773	IgE from pooled serum of Pecan allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	EQHRRQQQHQQR	Sequential / Linear	208-219	-	157218	IgE from pooled serum of Pecan allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	FDAEFLADAFNV	Sequential / Linear	238-249	-	157230	IgE from pooled serum of Pecan allergic patients	-	-	Strongly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	ERRQSRRGGRDD	Sequential / Linear	304-315	-	157220	IgE from pooled serum of Pecan allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	LNAHSVVYALRG	Sequential / Linear	382-393	-	157603	IgE from pooled serum of Pecan allergic patients	-	-	Moderately reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	GRQQHKFGQCQL	Sequential / Linear	28-39	-	157343	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	SQQGQRREFQQD	Sequential / Linear	124-135	-	158291	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	GQRREFQQDRHQ	Sequential / Linear	127-138	-	157340	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	QQDRHQKIRHFR	Sequential / Linear	133-144	-	157808	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	QEYEQHRRQQQH	Sequential / Linear	205-216	-	157770	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	NNVFSGFDAEFL	Sequential / Linear	232-243	-	157725	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	FSGFDAEFLADA	Sequential / Linear	235-246	-	157280	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	HSVVYALRGRAE	Sequential / Linear	385-396	-	157381	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	PQNFAVVKRARD	Sequential / Linear	421-432	-	157762	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-
Car i 4	Car i 4.0101	FAVVKRARDEGF	Sequential / Linear	424-435	-	157228	IgE from pooled serum of Pecan allergic patients	-	-	Weakly reacting epitope	Western / Immunoblot	21718052	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

Allergen	Cross-reactive Allergens	Reference
Car i 4	Jug r 4 (View AllerBase Entry)	21718052