Database of 2313 Experimentally Validated Allergens
Data for Can f 7
WHO/IUIS recognized Allergen

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AllerBase IDAB_A_00416Allergen NameCan f 7
Source OrganismCanis lupus familiaris (Dog)KingdomAnimal
Biological Function/RoleNPC2 family proteinMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS) 
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray 
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Can f 7:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Can f 7.0101Epididymal secretory protein E1
S77411.1  (View Sequence)AAB34263.1  (View Sequence)Q28895  (View Sequence)
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Sequence Analysis

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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome11896
AllFamAF111

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Can f 7Can f 7.0101TYSYLNKLPVKNSequential / Linear106-117-871379Serum from Dog-allergic children---ELISA30664181-
Can f 7Can f 7.0101PSIKLVVQWSequential / Linear120-128-871006Serum from Dog-allergic children---ELISA30664181-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Can f 7Fel d NPC2   (View AllerBase Entry)33191681