Database of 2313 Experimentally Validated Allergens
Data for Bos d 9
WHO/IUIS recognized Allergen

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Completeness Index: Denotes availibility of data for the allergen in Binary format
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0: data not available
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AllerBase IDAB_A_00358Allergen NameBos d 9
Source OrganismBos taurus (Cattle)KingdomAnimal
Biological Function/RoleMilk proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Bos d 9:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Bos d 9.0101Alpha-S1-casein
NM_181029  (View Sequence)NP_851372  (View Sequence)P02662  (View Sequence)
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Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Bos d 9 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome2734
AllFamAF065

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Bos d 9Bos d 9.0101NENLLRFFVAPFPEVFGKEKSequential / Linear32-51-43705IgE from serum of patients with cow's milk allergy--Major epitopeELISA11174208-
Bos d 9Bos d 9.0101KEDVPSERYLGYLEQLLRLKSequential / Linear98-117-30334IgE from serum of patients with cow's milk allergy--Major epitopeELISA11174208-
Bos d 9Bos d 9.0101LEIVPNSAEERLSequential / Linear124-135-35530IgE from serum of patients with cow's milk allergy--Major epitopeELISA and Western / Immunoblot11174208-
Bos d 9Bos d 9.0101NQELAYFYPELFRQFSequential / Linear154-168-45541IgE from serum of patients with cow's milk allergy--Major epitopeELISA11174208-
Bos d 9Bos d 9.0101YPSGAWYYVPLGTQYTSequential / Linear174-189-75411IgE from serum of patients with cow's milk allergy--Major epitopeELISA11174208-
Bos d 9Bos d 9.0101YTDAPSFSDIPNPIGSENSEKTSequential / Linear188-209-75992IgE from serum of patients with cow's milk allergy--Major epitopeELISA11174208-
Bos d 9Bos d 9.0101ELSKDIGSESSequential / Linear54-63-13272IgE from serum of patients with cow's milk allergy--Minor epitopeELISA11174208-
Bos d 9Bos d 9.0101EEIVPNSVEQSequential / Linear84-93-11704IgE from serum of patients with cow's milk allergy--Minor epitopeELISA11174208-
Bos d 9Bos d 9.0101MKEGIHAQQKSequential / Linear138-147-41811IgE from serum of patients with cow's milk allergy--Minor epitopeELISA and Western / Immunoblot11174208-
Bos d 9Bos d 9.0101EEIVPNSVEQSequential / Linear84-93-11704IgE from serum of patients with persistent cow's milk allergy---Western / Immunoblot11678861-
Bos d 9Bos d 9.0101ELSKDIGSESSequential / Linear54-63-13272IgE from serum of patients with persistent cow's milk allergy---Western / Immunoblot12170271-
Bos d 9Bos d 9.0101MKEGIHAQQKSequential / Linear138-147-41811IgE from serum of patients with persistent cow's milk allergy---Western / Immunoblot12170271-
Bos d 9Bos d 9.0101NENLLRFFVAPFPESequential / Linear32-45-43704IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101FFVAPFPEVFGKEKSequential / Linear38-51-15931IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101ERYLGYLEQLLRLKSequential / Linear104-117-14100IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101LEIVPNSAEERLSequential / Linear124-135-35530IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101NQELAYFYPELFRQSequential / Linear154-167-45540IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101YPSGAWYYVPLGTQSequential / Linear174-187-75410IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101YTDAPSFSDIPNPISequential / Linear188-201-75991IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101FSDIPNPIGSENSESequential / Linear194-207-17690IgE from serum of patients with cow's milk allergy--Major epitopeWestern / Immunoblot12897753-
Bos d 9Bos d 9.0101LNENLLRFFVAPFPEVFGKESequential / Linear31-50-38207IgE from serum of patients with cow's milk allergy--Immunodominant epitopeFluorescence Immuno Assay and Antigen Competition15541041-
Bos d 9Bos d 9.0101IGVNQELAYFYPELFRQFYQSequential / Linear151-170-26341IgE from serum of patients with cow's milk allergy--Immunodominant epitopeFluorescence Immuno Assay and Antigen Competition15541041-
Bos d 9Bos d 9.0101FPEVFGKEKVNELSKDIGSESTESequential / Linear43-65-78158IgE from serum of patients with cow's milk allergy---Microarray18774394-
Bos d 9Bos d 9.0101IKHQGLPQEVLNENLSequential / Linear21-35-190448IgE from serum of patients with cow's milk allergy--Immunodominant epitopeELISA24035023-
Bos d 9Bos d 9.0101LPQEVLNENLLRFFVSequential / Linear25-40-190475IgE from serum of patients with cow's milk allergy--Immunodominant epitopeELISA24035023-
Bos d 9Bos d 9.0101VEQKHIQKEDVPSERSequential / Linear91-105-190571IgE from serum of patients with cow's milk allergy--Immunodominant epitopeELISA24035023-
Bos d 9Bos d 9.0101GIHAQQKEPMIGVNQSequential / Linear141-155-190431IgE from serum of patients with cow's milk allergy--Immunodominant epitopeELISA24035023-
Bos d 9Bos d 9.0101TQYTDAPSFSDIPNPSequential / Linear186-200-190562IgE from serum of patients with cow's milk allergy--Immunodominant epitopeELISA24035023-
Bos d 9Bos d 9.0101NLLRFFVAPFPESequential / Linear34-45--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Gly m 5 cross-reactive epitope
Bos d 9Bos d 9.0101YLGYLEQLLRSequential / Linear96-105--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Gly m 5 cross-reactive epitope
Bos d 9Bos d 9.0101QLLRLKKYKVPQLESequential / Linear112-125--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Gly m 5 cross-reactive epitope
Bos d 9Bos d 9.0101RPKHPIKHQGLPQEVLNESequential / Linear16-33--Alpha casein-specific mAb 1D5---Dot blot, MALDI-TOF MS28643898Gly m 5 cross-reactive epitope
Bos d 9Bos d 9.0101EDVPSERSequential / Linear99-105--Serum of cow milk-allergic patients---Dot blot36307246-
Bos d 9Bos d 9.0101EGIHAQQKSequential / Linear140-147--Serum of cow milk-allergic patients---Dot blot36307246-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Bos d 9Gly m 5   (View AllerBase Entry)28643898
Bos d 9Cap h a-CSN  (View AllerBase Entry)
Ovi a a-CSN  (View AllerBase Entry)
9140519