Database of 2313 Experimentally Validated Allergens
Data for Bos d 4
WHO/IUIS recognized Allergen

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AllerBase IDAB_A_00353Allergen NameBos d 4
Source OrganismBos taurus (Cattle)KingdomAnimal
Biological Function/RoleAlbuminMode of ExposureIngestion, Inhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test  (Reference/s)ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test  (Reference/s)Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test  (Reference/s)Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay  (Reference/s)
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Bos d 4:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Bos d 4.0101Alpha-lactalbumin
M18780.1  (View Sequence)AAA30615.1  (View Sequence)P00711  (View Sequence)
1F6R 1F6S 1HFZ 
2G4N 		1f6r  1f6s  1hfz  
2g4n  

Sequence Analysis

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  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Bos d 4 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome163
AllFamAF016

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Bos d 4Bos d 4.0101EQLTKCEVFRELKDLKSequential / Linear20-351F6R  1F6S  1HFZ  
2G4N  		-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 4Bos d 4.0101KDLKGYGGVSLPEWSequential / Linear32-451F6R  1F6S  1HFZ  
2G4N  		-IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 4Bos d 4.0101STEYGLFQINNKSequential / Linear66-771F6R  1F6S  1HFZ  
2G4N  		115498IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 4Bos d 4.0101KKILDKVGINSequential / Linear112-1211F6R  1F6S  1HFZ  
2G4N  		115317IgE from serum of patients with cow's milk allergy---Western / Immunoblot11729348-
Bos d 4Bos d 4.0101KCEVFRELKDLKGYSequential / Linear24-371F6R  1F6S  1HFZ  
2G4N  		30052IgE from serum of patients with cow's milk allergy---Radio Immuno Assay1720415-
Bos d 4Bos d 4.0101EQLTKCEVFRELKDLSequential / Linear20-341F6R  1F6S  1HFZ  
2G4N  		558421IgE from serum of cow milk-allergic patients---ELISA27603546-
Bos d 4Bos d 4.0101CEVFRELKDLKGYGGSequential / Linear25-391F6R  1F6S  1HFZ  
2G4N  		558390IgE from serum of cow milk-allergic patients---ELISA27603546-
Bos d 4Bos d 4.0101DSTEYGLFQINNKIWSequential / Linear65-791F6R  1F6S  1HFZ  
2G4N  		558411IgE from serum of cow milk-allergic patients---ELISA27603546-
Bos d 4Bos d 4.0101NICNISCDKFLDDDLSequential / Linear90-1041F6R  1F6S  1HFZ  
2G4N  		558465IgE from serum of cow milk-allergic patients---ELISA27603546-
Bos d 4Bos d 4.0101INYWLAHKALCSEKLSequential / Linear120-1341F6R  1F6S  1HFZ  
2G4N  		558436IgE from serum of cow milk-allergic patients---ELISA27603546-
Bos d 4Bos d 4.0101DDQNPHSSNICNISCDKSequential / Linear82-982G4N  -Serum of cow milk-allergic patients---Dot blot36307246-
Bos d 4Bos d 4.0101FLDDDLTDDIMCVKSequential / Linear99-1122G4N  -Serum of cow milk-allergic patients---Dot blot36307246-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Bos d 4Bos d 5   (View AllerBase Entry)1720415
Bos d 4Hom s ALA   (View AllerBase Entry)DOI:10.1080/09540109999852