Database of 2313 Experimentally Validated Allergens
Data for Bos d 10
WHO/IUIS recognized Allergen

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0: data not available
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AllerBase IDAB_A_00348Allergen NameBos d 10
Source OrganismBos taurus (Cattle)KingdomAnimal
Biological Function/RoleMilk proteinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis 
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Bos d 10:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Bos d 10.0101Alpha-S2-casein
NM_174528  (View Sequence)NP_776953  (View Sequence)P02663  (View Sequence)
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Sequence Analysis

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  • BLAST Nucleotide/Protein sequence of Allergen Bos d 10 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome2735
AllFamAF065

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Bos d 10Bos d 10.0101YQKFALPQYLSequential / Linear186-195-75506IgE from serum of patients with persistent cow's milk allergy---Western / Immunoblot12170271-
Bos d 10Bos d 10.0101NEINQFYQKFPQYLQYLYSequential / Linear98-115--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Major epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101STEVFTKKTKLTEEEKSequential / Linear158-173--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Major epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101EKNRLNFLKKISQRYQSequential / Linear172-187--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Major epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101KKISQRYQKFALPQYLKTVYQHQKSequential / Linear180-203--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Major epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101SKENLCSTFCKEVVSequential / Linear46-59--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101VVRNANEEEYSIGSSequential / Linear58-71--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101PQYLQYLYQGPIVLSequential / Linear108-121--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101VLNPWDQVKRSequential / Linear120-129--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101VPITPTLNREQLSequential / Linear132-143--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101KPWIQPKTKVSequential / Linear206-215--Serum from patients with IgE mediated cow's milk allergy and atopic dermatitis--Minor epitopeWestern / Immunoblot12373003-
Bos d 10Bos d 10.0101KNTMEHVSSSEESIISQETYKQEKNMAINPSKSequential / Linear16-47-78187IgE from serum of patients with cow's milk allergy---Microarray18774394-
Bos d 10Bos d 10.0101EEVKITVDDKHYQKALNEINSequential / Linear82-101-78138IgE from serum of patients with cow's milk allergy---Microarray18774394-
Bos d 10Bos d 10.0101KTVYQHQKAMKPWIQPKTKVIPYVRYLSequential / Linear196-222-78189IgE from serum of patients with cow's milk allergy---Microarray18774394-
Bos d 10Bos d 10.0101NMAINPSKSequential / Linear40-47--Serum of cow milk-allergic patients---Dot blot36307246-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data


No Cross-Reactivity Data Available