Database of 2313 Experimentally Validated Allergens

Data for Bet v 6
WHO/IUIS recognized Allergen

1  1  1  0  1  0  0  1  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
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0: data not available
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AllerBase IDAB_P_00294Allergen NameBet v 6
Source OrganismBetula pendula (European white birch)KingdomPlant
Biological Function/RoleIsoflavone reductaseMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay 
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS) 
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray 
Radio Immunoassay 
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Bet v 6:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Bet v 6.0101Isoflavone reductase homolog Bet v 6.0101
AF135127.1  (View Sequence)AAC05116.2  (View Sequence)O65002  (View Sequence)
Bet v 6.0102Allergenic isoflavone reductase-like protein Bet v 6.0102AF282850.1  (View Sequence)AAG22740.1  (View Sequence)Q9FUW6  (View Sequence)

Sequence Analysis

  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Bet v 6 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

    Set E-value of your choice:    


  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Bet v 6:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)


    *Input your Nucleotode or Protein sequence (in FASTA format) here:


Cross-links to Allergen Databases


IgE Epitope Data

No Epitope Data Available

IgE Antibody Data

Antibody data Allergen data
Antibody/ Chain Description Clone/ Isolate Antibody Source IMGT NCBI Protein (GenPept) Broad Allergen Category Allergen Id /Name Material used for Sensitization Allergic Disease Antibody studied in Reference
IgE heavy chain mAb mP 36-Mus musculusAF518232AAP80683.1RespiratoryBet v 6Birch pollen extract, recombinant Bet v 1, recombinant Bet v 6Not specifiedNot specified12789227
IgE heavy chain mAb mP 34-Mus musculusAF518236AAP80687.1RespiratoryBet v 6Birch pollen extract, recombinant Bet v 1, recombinant Bet v 6Not specifiedNot specified12789227

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Bet v 6Pyr c 5   (View AllerBase Entry)11606193
Bet v 6Pis s IFR   (View AllerBase Entry)9519865