Database of 2313 Experimentally Validated Allergens

Data for Ana o 1
WHO/IUIS recognized Allergen

0  1  1  1  1  1  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_P_00103Allergen NameAna o 1
Source OrganismAnacardium occidentale (Cashew)KingdomPlant
Biological Function/RoleVicilinMode of ExposureIngestion

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test EAST Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test Crossed immunoelectrophoresis Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test 
Skin Test Microarray  (Reference/s)
Radio Immunoassay 
RAST 
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Ana o 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Ana o 1.0101Vicilin-like protein
AF395894.1  (View Sequence)AAM73730.2  (View Sequence)Q8L5L5  (View Sequence)
--
Ana o 1.0102Vicilin-like proteinAF395893.1  (View Sequence)AAM73729.1  (View Sequence)Q8L5L6  (View Sequence)
7UV1 7UV2 7uv1  7uv2  

Sequence Analysis

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  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Ana o 1 with Nucleotide or Protein sequences in AllerBase:
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Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome34
AllFamAF045

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Ana o 1Ana o 1.0101AIMGPPTKFSFSLFLSequential / Linear-2023IgE from serum of cashew allergic patients--Immunodominant epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101KECEKYYKEKKGRERSequential / Linear55-69-30318IgE from serum of cashew allergic patients--Immunodominant epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101EEFFFQGPEWRKEKESequential / Linear519-533-11615IgE from serum of cashew allergic patients--Immunodominant epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101CKVQRQYDEQQKEQCSequential / Linear39-53-6532IgE from serum of cashew allergic patients--Weakly binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101EQQKEQCVKECEKYYSequential / Linear47-61-13908IgE from serum of cashew allergic patients--Weakly binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101EKKGREREHEEEEEESequential / Linear63-77-12729IgE from serum of cashew allergic patients--Moderately binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101DEAEEEDENPYVFEDSequential / Linear143-157-7902IgE from serum of cashew allergic patients--Strongly binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101RRGEGPKIWPFTEESSequential / Linear335-349-55567IgE from serum of cashew allergic patients--Moderately binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101NITKGGMSVPFYNSRSequential / Linear391-405-44369IgE from serum of cashew allergic patients--Weakly binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101TKIAIVVSGEGCVEISequential / Linear407-421-64582IgE from serum of cashew allergic patients--Weakly binding epitopeRadio Immuno Assay12110836-
Ana o 1Ana o 1.0101SSHPSYKKLRARIRKSequential / Linear431-445-61072IgE from serum of cashew allergic patients--Weakly binding epitopeRadio Immuno Assay12110836-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Ana o 1Ara h 1  (View AllerBase Entry)
Jug r 2  (View AllerBase Entry)
Cor a 11  (View AllerBase Entry)
18029017
Ana o 1Pis v 3   (View AllerBase Entry)18479490
Ana o 1Ana o 2  (View AllerBase Entry)
Ana o 3  (View AllerBase Entry)
36331131