AllerBase Allergen Database

Data for Amb a 3

WHO/IUIS recognized Allergen

1 1 1 0 1 0 1 0 0

Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available

(Read More)

AllerBase ID	AB_P_00086	Allergen Name	Amb a 3
Source Organism	Ambrosia artemisiifolia (Short ragweed)	Kingdom	Plant
Biological Function/Role	Plastocyanin	Mode of Exposure	Inhalation

Assays/Methods used for Experimental Characterization (Read More)

: Data Available

: Data not Available

Biological assay / test	IgE assay / test	Physicochemical test	Cell-based assay
Basophil/Mast cell/Histamine Test	EAST	Chromatography (Reference/s)	Lymphocyte proliferation assay
Bronchial Test	ELISA (Reference/s)	Isoelectrofocusing
Conjunctival Test	Crossed immunoelectrophoresis (Reference/s)	Mass spectrometry (MS) (Reference/s)
Nasal Test	Fluorescence Immunoassay	N-terminal sequencing/sequence analysis
Oral Test	Immunochemiluminescent assay
Passive Cutaneous Anaphylaxis (PCA)	ImmunoCAP Test
Skin Test (Reference/s)	Microarray
	Radio Immunoassay
	RAST (Reference/s)
	Western/Immunoblot (Reference/s)

Isoallergen/Variant for Amb a 3:

Available

Isoallergen/Variant	Common Name	GenBank Nucleotide	NCBI Protein (GenPept)	UniProtKB	RCSB-PDB (Click on the PDB id to view structure)	ETR (Evolutionary Trace analysis Report)
Amb a 3.0101	Pollen allergen Amb a 3	-	P00304 (View Sequence)	P00304 (View Sequence)	-	-

Sequence Analysis

BLAST Nucleotide/Protein sequence of Allergen Amb a 3 with Nucleotide or Protein sequences in AllerBase:
Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table

Default E-value cut-off for BLAST is set at 0.01.

OR
Set E-value of your choice:
Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Amb a 3: (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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Cross-links to Allergen Databases

IgE Epitope Data

Allergen	Isoallergen / Isoform	Epitope	Type of Epitope	Sequence Position	View on Structure	IEDB	Antibody Used	IMGT	AgAbDb Link	Nature of Epitope	Assay	Reference	Comment
Amb a 3	Amb a 3.0101	GKVYLVGGPELGGWK	Sequential / Linear	1-15	-	20726	IgE from serum of patients allergic to ragweed	-	-	Immunodominant epitope	Radio Immuno Assay	2410296	-
Amb a 3	Amb a 3.0101	RAYALWSARQQFKTT	Sequential / Linear	21-35	-	53247	IgE from serum of patients allergic to ragweed	-	-	Immunodominant epitope	Radio Immuno Assay	2410296	-
Amb a 3	Amb a 3.0101	QFKTTDVLWFNFTTG	Sequential / Linear	31-45	-	50795	IgE from serum of patients allergic to ragweed	-	-	Immunodominant epitope	Radio Immuno Assay	2410296	-
Amb a 3	Amb a 3.0101	EVWREEAYHACDIKD	Sequential / Linear	51-65	-	14906	IgE from serum of patients allergic to ragweed	-	-	Immunodominant epitope	Radio Immuno Assay	2410296	-
Amb a 3	Amb a 3.0101	PGGPDRFTLLTPGSH	Sequential / Linear	71-85	-	47669	IgE from serum of patients allergic to ragweed	-	-	-	Radio Immuno Assay	2410296	-

IgE Antibody Data

No IgE Antibody Data Available

Cross-reactivity Data

No Cross-Reactivity Data Available