Database of 2313 Experimentally Validated Allergens
Data for Alt a 1
WHO/IUIS recognized Allergen

1  1  1  1  1  1  1  0  1 
Completeness Index: Denotes availibility of data for the allergen in Binary format
1: data available
0: data not available
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AllerBase IDAB_F_00064Allergen NameAlt a 1
Source OrganismAlternaria alternata (Alternaria rot fungus)KingdomFungi
Biological Function/RoleUnknownMode of ExposureInhalation

Assays/Methods used for Experimental Characterization (Read More)

  :  Data Available    : Data not Available

Biological assay / test IgE assay / test Physicochemical test Cell-based assay
Basophil/Mast cell/Histamine Test  (Reference/s)EAST  (Reference/s)Chromatography  (Reference/s)Lymphocyte proliferation assay  (Reference/s)
Bronchial Test  (Reference/s)ELISA  (Reference/s)Isoelectrofocusing 
Conjunctival Test  (Reference/s)Crossed immunoelectrophoresis  (Reference/s)Mass spectrometry (MS)  (Reference/s)
Nasal Test Fluorescence Immunoassay  (Reference/s)N-terminal sequencing/sequence analysis  (Reference/s)
Oral Test Immunochemiluminescent assay 
Passive Cutaneous Anaphylaxis (PCA) ImmunoCAP Test  (Reference/s)
Skin Test  (Reference/s)Microarray  (Reference/s)
Radio Immunoassay  (Reference/s)
RAST  (Reference/s)
Western/Immunoblot  (Reference/s)

Isoallergen/Variant for Alt a 1:Available

Isoallergen/Variant Common Name GenBank Nucleotide NCBI Protein (GenPept) UniProtKB RCSB-PDB (Click on the PDB id to view structure) ETR (Evolutionary Trace analysis Report)
Alt a 1.0101Major allergen Alt a 1
U86752.1  (View Sequence)AAB47552.1  (View Sequence)P79085  (View Sequence)
3V0R 4AUD 3v0r  4aud  
Alt a 1.0101Allergen Alt a I subunitU82633.1  (View Sequence)AAB40400.1  (View Sequence)---
Alt a 1.0102Major allergen Alt a 1 subunitAY568627.1  (View Sequence)AAS75297.1  (View Sequence)Q6Q128  (View Sequence)
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Sequence Analysis

  • BLAST
  • Pairwise alignment
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  • BLAST Nucleotide/Protein sequence of Allergen Alt a 1 with Nucleotide or Protein sequences in AllerBase:
    Select GenBank or UniprotKB accession number by clicking on the checkbox in the above table  

    Default E-value cut-off for BLAST is set at 0.01.

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    Set E-value of your choice:    

       

  • Align Nucleotode/Protein sequence of Your choice with Nucleotode or Protein sequence of Allergen Alt a 1:  (Alignment job will be redirected to EMBL-EMBOSS Water or Needle tool)

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    *Input your Nucleotode or Protein sequence (in FASTA format) here:

        


Cross-links to Allergen Databases

IUISIUIS-Allergen
Allergome722
AllFamAF196

IgE Epitope Data

Allergen Isoallergen / Isoform Epitope Type of Epitope Sequence Position View on Structure IEDB Antibody Used IMGT AgAbDb Link Nature of Epitope Assay Reference Comment
Alt a 1Alt a 1.0101KISEFYGRKPSequential / Linear41-503V0R  4AUD  101790IgE from serum of patients with Alternaria-induced allergy--Major epitopeWestern / Immunoblot12668200-
Alt a 1Alt a 1.0101YYNSLGFNIKSequential / Linear54-633V0R  4AUD  102271IgE from serum of patients with Alternaria-induced allergy--Major epitopeWestern / Immunoblot12668200-
Alt a 1Alt a 1.0101YSCGENSFMDSequential / Linear87-963V0R  4AUD  102265IgE from serum of patients with Alternaria-induced allergy---Western / Immunoblot12668200-
Alt a 1Alt a 1.0101VATATLPNYCSequential / Linear119-1283V0R  4AUD  102169IgE from serum of patients with Alternaria-induced allergy---Western / Immunoblot12668200-

IgE Antibody Data


No IgE Antibody Data Available

Cross-reactivity Data

Allergen Cross-reactive Allergens Reference
Alt a 1Ste b 1  (View AllerBase Entry)
Ulo b 1  (View AllerBase Entry)
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