References/Publications for Lymphocyte proliferation assay of Phl p 5

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8634519 Int Arch Allergy Immunol. 1996 Apr;109(4):352-5.

Group 5 allergens of timothy grass (Phl p 5) bear cross-reacting T cell epitopes
with group 1 allergens of rye grass (Lol p 1).

Müller WD(1), Karamfilov T, Bufe A, Fahlbush B, Wolf I, Jäger L.


9500758 J Allergy Clin Immunol. 1998 Feb;101(2 Pt 1):241-9.

Dissection of the grass allergen-specific immune response in patients with
allergies and control subjects: T-cell proliferation in patients does not
correlate with specific serum IgE and skin reactivity.

Würtzen PA(1), van Neerven RJ, Arnved J, Ipsen H, Sparholt SH.


17359394 Clin Exp Allergy. 2007 Mar;37(3):441-50.

Generation of a low immunoglobulin E-binding mutant of the timothy grass pollen
major allergen Phl p 5a.

Wald M(1), Kahlert H, Weber B, Jankovic M, Keller W, Cromwell O, Nandy A, Fiebig
H.


20150742 Int Arch Allergy Immunol. 2010;152(3):243-54. doi: 10.1159/000283033. Epub 2010
Feb 11.

The T cell response to major grass allergens is regulated and includes IL-10
production in atopic but not in non-atopic subjects.

Domdey A(1), Liu A, Millner A, Lund K, Jacobi H, Malling HJ, Søndergaard I,
Würtzen PA.


22653364 Int Arch Allergy Immunol. 2012;159(2):130-42. doi: 10.1159/000336651. Epub 2012
May 30.

Hypoallergenic mutants of the Timothy grass pollen allergen Phl p 5 generated by
proline mutations.

Wald M(1), Kahlert H, Reese G, Krontal N, Zafred D, Keller W, Cromwell O, Fiebig
H, Nandy A.


23765421 Eur J Immunol. 2013 Sep;43(9):2451-60. doi: 10.1002/eji.201243277. Epub 2013 Jul


The site of allergen expression in hematopoietic cells determines the degree and
quality of tolerance induced through molecular chimerism.

Baranyi U(1), Gattringer M, Farkas AM, Hock K, Pilat N, Iacomini J, Valenta R,
Wekerle T.


24182774 J Allergy Clin Immunol. 2014 Mar;133(3):836-45.e11. doi:
1016/j.jaci.2013.08.038. Epub 2013 Oct 31.

Dissection of the IgE and T-cell recognition of the major group 5 grass pollen
allergen Phl p 5.

Focke-Tejkl M(1), Campana R(2), Reininger R(3), Lupinek C(2), Blatt K(4), Valent
P(4), Pavkov-Keller T(5), Keller W(5), Valenta R(6).


25441634 J Allergy Clin Immunol. 2015 May;135(5):1207-7.e1-11. doi:
1016/j.jaci.2014.09.012. Epub 2014 Nov 13.

Development and characterization of a recombinant, hypoallergenic, peptide-based
vaccine for grass pollen allergy.

Focke-Tejkl M(1), Weber M(1), Niespodziana K(1), Neubauer A(2), Huber H(2),
Henning R(2), Stegfellner G(2), Maderegger B(2), Hauer M(2), Stolz F(2),
Niederberger V(3), Marth K(1), Eckl-Dorna J(3), Weiss R(4), Thalhamer J(4), Blatt
K(5), Valent P(5), Valenta R(6).


26687027 Allergy. 2016 Apr;71(4):495-504. doi: 10.1111/all.12824. Epub 2016 Jan 26.

Standardization of allergen products: 2. Detailed characterization of
GMP-produced recombinant Phl p 5.0109 as European Pharmacopoeia reference
standard.

Himly M(1), Nandy A(2), Kahlert H(2), Thilker M(2), Steiner M(1), Briza P(1),
Neubauer A(3), Klysner S(2), van Ree R(4), Buchheit KH(5), Vieths S(6), Ferreira
F(1).