References/Publications for Basophil/Mast cell_Histamine Test of Phl p 5

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7542075 Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):242-4.

Molecular characterization of timothy grass pollen group V allergens.

Becker WM(1), Bufe A, Petersen A, Schlaak M.


7691956 J Immunol. 1993 Nov 1;151(9):4773-81.

cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen;
characterization of the recombinant Phl pV allergen.

Vrtala S(1), Sperr WR, Reimitzer I, van Ree R, Laffer S, Müller WD, Valent P,
Lechner K, Rumpold H, Kraft D, et al.


8613635 J Allergy Clin Immunol. 1996 Mar;97(3):781-7.

Immunologic characterization of purified recombinant timothy grass pollen (Phleum
pratense) allergens (Phl p 1, Phl p2, Phl p 5).

Vrtala S(1), Susani M, Sperr WR, Valent P, Laffer S, Dolecek C, Kraft D, Valenta
R.


9973522 J Immunol. 1999 Feb 15;162(4):2406-14.

"Allergen engineering": variants of the timothy grass pollen allergen Phl p 5b
with reduced IgE-binding capacity but conserved T cell reactivity.

Schramm G(1), Kahlert H, Suck R, Weber B, Stüwe HT, Müller WD, Bufe A, Becker WM,
Schlaak MW, Jäger L, Cromwell O, Fiebig H.


11003446 Allergy. 2000 Sep;55(9):827-35.

Allergen-specific immunotherapy in birch- and grass-pollen-allergic rhinitis. II.
Side-effects.

Winther L(1), Malling HJ, Mosbech H.


11034391 J Immunol. 2000 Oct 1;165(7):3849-59.

A human monoclonal IgE antibody defines a highly allergenic fragment of the major
timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural
characterization of the epitope-containing domain.

Flicker S(1), Vrtala S, Steinberger P, Vangelista L, Bufe A, Petersen A,
Ghannadan M, Sperr WR, Valent P, Norderhaug L, Bohle B, Stockinger H, Suphioglu
C, Ong EK, Kraft D, Valenta R.


11421902 Allergy. 2001 Jun;56(6):548-52.

Diagnostic evaluation of grass- and birch-allergic patients with oral allergy
syndrome.

Anhoej C(1), Backer V, Nolte H.


16950295 J Allergy Clin Immunol. 2006 Sep;118(3):734-41. Epub 2006 Jun 6.

Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively
prevents allergic sensitization.

Gabler M(1), Scheiblhofer S, Kern K, Leitner WW, Stoecklinger A,
Hauser-Kronberger C, Alinger B, Lechner B, Prinz M, Vrtala S, Valenta R,
Thalhamer J, Weiss R.


17070909 Mol Immunol. 2007 Mar;44(8):1879-87. Epub 2006 Oct 30.

Gene gun immunization with clinically relevant allergens aggravates allergen
induced pathology and is contraindicated for allergen immunotherapy.

Scheiblhofer S(1), Stoecklinger A, Gruber C, Hauser-Kronberger C, Alinger B,
Hammerl P, Thalhamer J, Weiss R.


17359394 Clin Exp Allergy. 2007 Mar;37(3):441-50.

Generation of a low immunoglobulin E-binding mutant of the timothy grass pollen
major allergen Phl p 5a.

Wald M(1), Kahlert H, Weber B, Jankovic M, Keller W, Cromwell O, Nandy A, Fiebig
H.


21720171 Int Arch Allergy Immunol. 2011;156(3):259-66. doi: 10.1159/000323733. Epub 2011
Jun 29.

Expression of a major plant allergen as membrane-anchored and secreted protein in
human cells with preserved T cell and B cell epitopes.

Baranyi U(1), Gattringer M, Boehm A, Marth K, Focke-Tejkl M, Bohle B, Blatt K,
Valent P, Valenta R, Wekerle T.


22185730 Am J Rhinol Allergy. 2011 Nov-Dec;25(6):e225-31. doi: 10.2500/ajra.2011.25.3723.

Reliability of basophil activation test using CD203c expression in diagnosis of
pollen allergy.

Özdemir SK(1), Güloğlu D, Sin BA, Elhan AH, Ikincioğulları A, Mısırlıgil Z.


22653364 Int Arch Allergy Immunol. 2012;159(2):130-42. doi: 10.1159/000336651. Epub 2012
May 30.

Hypoallergenic mutants of the Timothy grass pollen allergen Phl p 5 generated by
proline mutations.

Wald M(1), Kahlert H, Reese G, Krontal N, Zafred D, Keller W, Cromwell O, Fiebig
H, Nandy A.


23182706 Immunobiology. 2013 Jun;218(6):884-91. doi: 10.1016/j.imbio.2012.10.008. Epub
2012 Oct 26.

Passive immunization with allergen-specific IgG antibodies for treatment and
prevention of allergy.

Flicker S(1), Linhart B, Wild C, Wiedermann U, Valenta R.


23327896 Pharmeur Bio Sci Notes. 2012 Apr;2012:118-34.

Establishment of recombinant major allergens Bet v 1 and Phl p 5a as Ph. Eur.
reference standards and validation of ELISA methods for their measurement.
Results from feasibility studies.

Vieths S(1), Barber D, Chapman M, Costanzo A, Daas A, Fiebig H, Hanschmann KM,
Hrabina M, Kaul S, Ledesma A, Moingeon P, Reese G, Schörner C, van Ree R, Weber
B, Buchheit KH.


24182774 J Allergy Clin Immunol. 2014 Mar;133(3):836-45.e11. doi:
1016/j.jaci.2013.08.038. Epub 2013 Oct 31.

Dissection of the IgE and T-cell recognition of the major group 5 grass pollen
allergen Phl p 5.

Focke-Tejkl M(1), Campana R(2), Reininger R(3), Lupinek C(2), Blatt K(4), Valent
P(4), Pavkov-Keller T(5), Keller W(5), Valenta R(6).


26687027 Allergy. 2016 Apr;71(4):495-504. doi: 10.1111/all.12824. Epub 2016 Jan 26.

Standardization of allergen products: 2. Detailed characterization of
GMP-produced recombinant Phl p 5.0109 as European Pharmacopoeia reference
standard.

Himly M(1), Nandy A(2), Kahlert H(2), Thilker M(2), Steiner M(1), Briza P(1),
Neubauer A(3), Klysner S(2), van Ree R(4), Buchheit KH(5), Vieths S(6), Ferreira
F(1).