References/Publications for ImmunoCAP Test of Phl p 12

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11736747 Allergy. 2001 Dec;56(12):1180-5.

Measurement of IgE antibodies against purified grass-pollen allergens (Phl p 1,
2, 3, 4, 5, 6, 7, 11, and 12) in sera of patients allergic to grass pollen.

Rossi RE(1), Monasterolo G, Monasterolo S.

12534548 Clin Exp Allergy. 2003 Jan;33(1):43-51.

Skin test with a timothy grass (Phleum pratense) pollen extract vs. IgE to a
timothy extract vs. IgE to rPhl p 1, rPhl p 2, nPhl p 4, rPhl p 5, rPhl p 6, rPhl
p 7, rPhl p 11, and rPhl p 12: epidemiological and diagnostic data.

Mari A(1).

15286445 Int Arch Allergy Immunol. 2004 Sep;135(1):44-53. Epub 2004 Jul 30.

Evaluation of recombinant and native timothy pollen (rPhl p 1, 2, 5, 6, 7, 11, 12
and nPhl p 4)- specific IgG4 antibodies induced by subcutaneous immunotherapy
with timothy pollen extract in allergic patients.

Rossi RE(1), Monasterolo G.

15647039 Allergy. 2005 Feb;60(2):185-91.

Antibody profiles and self-reported symptoms to pollen-related food allergens in
grass pollen-allergic patients from northern Europe.

Ghunaim N(1), Grönlund H, Kronqvist M, Grönneberg R, Söderström L, Ahlstedt S,
van Hage-Hamsten M.

16174987 Int Arch Allergy Immunol. 2005 Oct;138(2):105-10. Epub 2005 Sep 19.

Possible relationship between systemic side effects and sensitization to rPar j 2
in allergic patients submitted to an ultra-rush (20 min) sublingual immunotherapy
and selected by component resolved diagnosis.

Rossi RE(1), Monasterolo G, Coco G, Operti D.

17039664 J Investig Allergol Clin Immunol. 2006;16(5):274-8.

Change in the pattern of IgE reactivity to timothy grass and birch pollen
allergens over a 20-year period.

Movérare R(1), Kosunen TU, Haahtela T.

18349590 Allergol Int. 2008 Jun;57(2):157-64. doi: 10.2332/allergolint.O-07-503.

IgE profiles of Bermuda grass pollen sensitised patients evaluated by Phleum
pratense allergens Phl P 1, 2, 4, 5, 6 , 7, 11, 12.

Rossi RE(1), Monasterolo G, Prina P, Coco G, Operti D, Rossi L.

20554959 J Immunol. 2010 Jul 15;185(2):943-55. doi: 10.4049/jimmunol.1000405. Epub 2010
Jun 16.

Molecular determinants of T cell epitope recognition to the common Timothy grass

Oseroff C(1), Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI,
Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A.

21789968 Eur Ann Allergy Clin Immunol. 2011 Jun;43(3):77-80.

Analysis of hypersensitivity to oleaceae pollen in an olive-free and ash-free
area by commercial pollen extracts and recombinant allergens.

Asero R(1).

22206774 J Allergy Clin Immunol. 2012 Mar;129(3):834-839.e8. doi:
1016/j.jaci.2011.10.045. Epub 2011 Dec 28.

Molecular profiles of IgE to Phleum pratense in children with grass pollen
allergy: implications for specific immunotherapy.

Tripodi S(1), Frediani T, Lucarelli S, Macrě F, Pingitore G, Di Rienzo Businco A,
Dondi A, Pansa P, Ragusa G, Asero R, Faggian D, Plebani M, Matricardi PM.

22360135 Eur Ann Allergy Clin Immunol. 2011 Dec;43(6):184-7.

Are anti-Phl p 12 IgE levels predictive of oral allergy syndrome in profilin
hypersensitive patients?

Asero R(1), Villalta D.

22526205 Allergol Int. 2012 Jun;61(2):339-46. doi: 10.2332/allergolint.11-OA-0372. Epub
2012 Apr 25.

Detection of Phl p 1, Phl p 5, Phl p 7 and Phl p 12 specific IgE antibodies in
the sera of children and adult patients allergic to Phleum pollen.

Sekerkova A(1), Polackova M, Striz I.

22694773 Clin Mol Allergy. 2012 Jun 13;10(1):7. doi: 10.1186/1476-7961-10-7.

Specific IgE response to different grass pollen allergen components in children
undergoing sublingual immunotherapy.

Marcucci F(1), Sensi L, Incorvaia C, Dell'Albani I, Di Cara G, Frati F.

22920078 Ann Allergy Asthma Immunol. 2012 Sep;109(3):215-9. doi:
1016/j.anai.2012.07.003. Epub 2012 Aug 1.

Profilin cross-reactive panallergen causes latex sensitization in the pediatric
population allergic to pollen.

Casquete-Román E(1), Rosado-Gil T, Postigo I, Guisantes JA, Fernández M, Torres
HE, Martínez-Quesada J.

24261946 Clin Exp Allergy. 2013 Dec;43(12):1362-73. doi: 10.1111/cea.12187.

Heterogeneity of antibody responses among clinical responders during grass pollen
sublingual immunotherapy.

Baron-Bodo V(1), Horiot S, Lautrette A, Chabre H, Drucbert AS, Danzé PM, Sénéchal
H, Peltre G, Galvain S, Zeldin RK, Horak F, Moingeon P.

24308506 Clin Mol Allergy. 2013 Dec 5;11(1):3. doi: 10.1186/1476-7961-11-3.

Association between a low IgE response to Phl p 5 and absence of asthma in
patients with grass pollen allergy.

Savi E(1), Peveri S, Incorvaia C, Dell'Albani I, Marcucci F, Di Cara G, Frati F.

26310043 J Investig Allergol Clin Immunol. 2015;25(4):283-7.

Do Skin Prick Test and In Vitro Techniques Diagnose Sensitization to Peach Lipid
Transfer Protein and Profilin Equally Well in Allergy to Plant Food and Pollen?

Goikoetxea MJ, Berroa F, Cabrera-Freitag P, Ferrer M, Núńez-Córdoba JM, Sanz ML,
Gastaminza G.

OBJECTIVE: To compare the skin prick test (SPT) with in vitro techniques (single
and multiplex fluorescence enzyme-immunoassay [FEIA]) for detecting sensitization
to profilin and lipid transfer protein (LTP).
METHODS: We retrospectively studied 181 patients with pollen and/or plant food
allergy and 61 controls. SPT was performed with date palm profilin (Pho d 2) and
peach LTP (Pru p 3), and specific IgE (sIgE) to Phl p 12 and Pru p 3 was analyzed
using single FEIA and microarray.
RESULTS: Fifteen of 201 patients with negative results for LTP in the SPT were
sensitized to this allergen in the in vitro tests, and 18 of 41 patients with
positive results for LTP in the SPT were not sensitized according to the in vitro
tests. Seventeen of 186 patients with negative results for profilin in the SPT
were sensitized to Phl p 12 by serum sIgE, and 30 out of 56 patients with
positive results for profilin in SPT were not sensitized to Phl p 12 according to
the other tests. Moderate agreement was observed between the 3 techniques
CONCLUSIONS: SPT is a sensitive technique for detecting sensitization to LTP and
profilin. Its results are similar to those of in vitro techniques, especially in
patients with negative SPT results for peach LTP and palm tree profilin.

PMID: 26310043 [Indexed for MEDLINE]
Clin Exp Allergy. 2014;44(5):778-86. doi: 10.1111/cea.12303.

Allergens. Heterogeneity of molecular sensitization profiles in grass pollen
allergy--implications for immunotherapy?

Darsow U(1), Brockow K, Pfab F, Jakob T, Petersson CJ, Borres MP, Ring J,
Behrendt H, Huss-Marp J.

24940475 World Allergy Organ J. 2014 May 8;7(1):11. doi: 10.1186/1939-4551-7-11.
eCollection 2014.

Immunological cross-reactivity between olive and grass pollen: implication of
major and minor allergens.

Cases B(1), Ibańez MD(2), Tudela JI(1), Sanchez-Garcia S(2), Del Rio PR(2),
Fernandez EA(1), Escudero C(2), Fernandez-Caldas E(1).

27614266 Mol Immunol. 2016 Oct;78:105-112. doi: 10.1016/j.molimm.2016.08.013. Epub 2016
Sep 8.

Major grass pollen allergens and components detected in a southern Chinese cohort
of patients with allergic rhinitis and/or asthma.

Luo W(1), Huang H(1), Zheng P(1), Wei N(1), Luo J(1), Sun B(2), Zeng G(3).

29055045 Allergy. 2018 Mar;73(3):673-682. doi: 10.1111/all.13338. Epub 2017 Dec 14.

Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum
pratense molecules.

Cipriani F(1)(2), Mastrorilli C(1)(3), Tripodi S(4), Ricci G(2), Perna S(1),
Panetta V(5), Asero R(6), Dondi A(7), Bianchi A(8), Maiello N(9), Miraglia Del
Giudice M(9), Frediani T(10), Macrě F(10), Lucarelli S(10), Dello Iacono I(11),
Patria MF(12), Varin E(13), Peroni D(14), Chini L(15), Moschese V(15), Bernardini
R(16), Pingitore G(17), Pelosi U(18), Tosca M(19), Paravati F(20), Sfika I(4),
Businco ADR(4), Povesi Dascola C(3), Comberiati P(14), Frediani S(10), Lambiase
C(10), Verga MC(21), Faggian D(22), Plebani M(22), Calvani M(8), Caffarelli C(3),
Matricardi PM(1); Italian Pediatric Allergy Network (I-PAN).

Allergol Immunopathol (Madr). 2019 Nov - Dec;47(6):579-584. doi:
1016/j.aller.2019.04.006. Epub 2019 Aug 30.

Sensitization to grass allergens: Phl p1, Phl p5 and Phl p7 Phl p12 in adult and
children patients in Beja (Southern Portugal).

Almeida E(1), Caeiro E(2), Todo-Bom A(3), Duarte A(4), Gazarini L(5).

33852622 PLoS One. 2021 Apr 14;16(4):e0249649. doi: 10.1371/journal.pone.0249649.
eCollection 2021.

Pollen-food allergy syndrome and component sensitization in adolescents: A
Japanese population-based study.

Kiguchi T(1), Yamamoto-Hanada K(1), Saito-Abe M(1), Sato M(1), Irahara M(1),
Ogita H(1), Miyagi Y(1), Inuzuka Y(1), Toyokuni K(1), Nishimura K(1), Ishikawa
F(1), Miyaji Y(1), Kabashima S(1), Fukuie T(1), Narita M(1), Ohya Y(1).

34079923 Allergol Select. 2021 May 27;5:180-186. doi: 10.5414/ALX02238E. eCollection 2021.

Molecular allergy diagnosis using pollen marker allergens and pollen
panallergens: Five patterns seen in multiple test reactions to pollen extracts.

Kleine-Tebbe J(1), Ackermann-Simon J(1), Hanf G(1).