References/Publications for RAST of Fel d 1

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7264307 J Immunol. 1981 Sep;127(3):972-5.

Allergenically active components of cat allergen extracts.

Anderson MC, Baer H.

The allergens involved in cat allergy have been studied in pelt extracts, saliva,
serum, and urine. Using crossed immunoelectrophoresis (CIE) to examine the
antigenic content, and crossed radioimmunoelectrophoresis (CRIE) and RAST to
examine the allergenic content, it was found that allergen 1 of Dr. Ohman is the
most important allergenic component, whereas albumin and several unidentified
proteins play a minor role. Allergen 1 was not detectable in serum and urine. The
allergenic and nonallergenic proteins of pelt extract and saliva were identical
by CIE, suggesting that pelt extract proteins are mainly of salivary origin.

PMID: 7264307 [Indexed for MEDLINE]
J Allergy Clin Immunol. 1988 Nov;82(5 Pt 1):778-86.

Monoclonal antibodies to the major feline allergen Fel d I. I. Serologic and
biologic activity of affinity-purified Fel d I and of Fel d I-depleted extract.

de Groot H(1), van Swieten P, van Leeuwen J, Lind P, Aalberse RC.

1282843 Int Arch Allergy Immunol. 1992;99(1):63-73.

Structure of the major cat allergen Fel d I in different allergen sources: an
immunoblotting analysis with monoclonal antibodies against denatured Fel d I and
human IgE.

van Milligen FJ(1), van Swieten P, Aalberse RC.

1695231 J Allergy Clin Immunol. 1990 Jul;86(1):107-16.

Evidence for a Fel d I-like molecule in the "big cats" (Felidae species).

de Groot H(1), van Swieten P, Aalberse RC.

1712068 Mol Immunol. 1991 Apr-May;28(4-5):301-9.

Studies on the biochemical structure of the major cat allergen Felis domesticus

Duffort OA(1), Carreira J, Nitti G, Polo F, Lombardero M.

2708737 J Allergy Clin Immunol. 1989 Apr;83(4):776-83.

Correlations between levels of mite and cat allergens in settled and airborne

Swanson MC(1), Campbell AR, Klauck MJ, Reed CE.

7508463 J Allergy Clin Immunol. 1994 Jan;93(1 Pt 1):34-43.

IgE epitopes on the cat (Felis domesticus) major allergen Fel d I: a study with
overlapping synthetic peptides.

van Milligen FJ(1), van 't Hof W, van den Berg M, Aalberse RC.

7560654 J Allergy Clin Immunol. 1995 Oct;96(4):449-56.

Quantitative assessment of exposure to dog (Can f 1) and cat (Fel d 1) allergens:
relation to sensitization and asthma among children living in Los Alamos, New

Ingram JM(1), Sporik R, Rose G, Honsinger R, Chapman MD, Platts-Mills TA.

7788572 Clin Exp Allergy. 1995 Mar;25(3):247-51.

Differences between specificities of IgE and IgG4 antibodies: studies using
recombinant chain 1 and chain 2 of the major cat allergen Felis domesticus (Fel
d) I.

Van Milligen FJ(1), Craig S, Rogers BL, Van Swieten P, Aalberse RC.

7797791 J Allergy Clin Immunol. 1995 Jun;95(6):1221-8.

IgE antibodies to recombinant forms of Fel d I: dichotomy between fluid-phase and
solid-phase binding studies.

Slunt JB(1), Rogers BL, Chapman MD.

8111245 Int Arch Allergy Immunol. 1994;103(3):274-9.

IgE and IgG4 binding to synthetic peptides of the cat (Felis domesticus) major
allergen Fel dI.

van Milligen FJ(1), van 't Hof W, Aalberse RC.

8232338 Mol Immunol. 1993 Nov;30(16):1529-41.

Native and recombinant Fel dI as probes into the relationship of allergen
structure to human IgE immunoreactivity.

Bond JF(1), Brauer AW, Segal DB, Nault AK, Rogers BL, Kuo MC.

8315287 J Immunol Methods. 1993 Jun 18;162(2):165-73.

Calculation of the affinity constant KASS for solid phase antigen. A model system
using monoclonal antibodies against the cat allergen Fel d I.

van Milligen FJ(1), van Etten L, Aalberse RC.

9088651 Clin Exp Allergy. 1997 Mar;27(3):252-61.

Allergen content in dust from homes and schools in northern Norway in relation to
sensitization and allergy symptoms in schoolchildren.

Dotterud LK(1), Van TD, Kvammen B, Dybendal T, Elsayed S, Falk ES.

10589005 J Allergy Clin Immunol. 1999 Dec;104(6):1223-30.

Purified natural and recombinant Fel d 1 and cat albumin in in vitro diagnostics
for cat allergy.

van Ree R(1), van Leeuwen WA, Bulder I, Bond J, Aalberse RC.

11253969 Lancet. 2001 Mar 10;357(9258):752-6.

Sensitisation, asthma, and a modified Th2 response in children exposed to cat
allergen: a population-based cross-sectional study.

Platts-Mills T(1), Vaughan J, Squillace S, Woodfolk J, Sporik R.

15647038 Allergy. 2005 Feb;60(2):177-84.

Exposure to pets, and the association with hay fever, asthma, and atopic
sensitization in rural children.

Waser M(1), von Mutius E, Riedler J, Nowak D, Maisch S, Carr D, Eder W, Tebow G,
Schierl R, Schreuer M, Braun-Fahrländer C; ALEX Study team.

18477016 Clin Exp Allergy. 2008 Aug;38(8):1275-81. doi: 10.1111/j.1365-2222.2008.03003.x.
Epub 2008 May 12.

Higher immunoglobulin E antibody levels to recombinant Fel d 1 in cat-allergic
children with asthma compared with rhinoconjunctivitis.

Grönlund H(1), Adédoyin J, Reininger R, Varga EM, Zach M, Fredriksson M,
Kronqvist M, Szepfalusi Z, Spitzauer S, Grönneberg R, Valenta R, Hedlin G, van
Hage M.

23268458 World Allergy Organ J. 2011 Jul;4(7):113-9. doi: 10.1097/WOX.0b013e3182228a39.
Epub 2011 Jul 14.

Glutaraldehyde-Modified Recombinant Fel d 1: A Hypoallergen With Negligible
Biological Activity But Retained Immunogenicity.

Versteeg SA(1), Bulder I, Himly M, van Capel TM, van den Hout R, Koppelman SJ, de
Jong EC, Ferreira F, van Ree R.