Select | PubMed ID | Description |
| 6886253 | J Allergy Clin Immunol. 1983 Aug;72(2):150-9.
Isolation and immunochemical characterization of the major allergen of birch pollen (Betula verrucosa).
Ipsen H, Løwenstein H.
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| 2807579 | Int Arch Allergy Appl Immunol. 1989;90(1):54-60.
Monoclonal antibodies against birch pollen allergens: characterization by immunoblotting and use for single-step affinity purification of the major allergen Bet v I.
Jarolim E(1), Tejkl M, Rohac M, Schlerka G, Scheiner O, Kraft D, Breitenbach M, Rumpold H.
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| 2101127 | Int Arch Allergy Appl Immunol. 1990;93(4):378-84.
Purification and N-terminal amino acid sequence of two birch pollen isoallergens (Bet v I and Bet v II).
Elsayed S(1), Vik H.
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| 1961201 | Mol Immunol. 1991 Nov;28(11):1279-88.
The NH2-terminal amino acid sequence of the immunochemically partial identical major allergens of Alder (Alnus glutinosa) Aln g I, birch (Betula verrucosa) Bet v I, hornbeam (Carpinus betulus) Car b I and oak (Quercus alba) Que a I pollens.
Ipsen H(1), Hansen OC.
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| 7852325 | J Biol Chem. 1995 Feb 10;270(6):2607-13.
Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid chromatography, mass spectrometry, and cDNA cloning.
Swoboda I(1), Jilek A, Ferreira F, Engel E, Hoffmann-Sommergruber K, Scheiner O, Kraft D, Breiteneder H, Pittenauer E, Schmid E, et al.
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| 8936599 | Protein Expr Purif. 1996 Nov;8(3):365-73.
Characterization of purified recombinant Bet v 1 with authentic N-terminus, cloned in fusion with maltose-binding protein.
Spangfort MD(1), Ipsen H, Sparholt SH, Aasmul-Olsen S, Larsen MR, Mørtz E, Roepstorff P, Larsen JN.
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| 9058694 | J Allergy Clin Immunol. 1997 Mar;99(3):374-84.
Immunologic characterization of monoclonal antibodies that modulate human IgE binding to the major birch pollen allergen Bet v 1.
Lebecque S(1), Dolecek C, Laffer S, Visco V, Denépoux S, Pin JJ, Guret C, Boltz-Nitulescu G, Weyer A, Valenta R.
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| 9116499 | Protein Expr Purif. 1997 Feb;9(1):33-9.
High-level expression and purification of the major birch pollen allergen, Bet v
Hoffmann-Sommergruber K(1), Susani M, Ferreira F, Jertschin P, Ahorn H, Steiner R, Kraft D, Scheiner O, Breiteneder H.
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| 9278148 | Biol Chem. 1997 Jul;378(7):687-95.
Expression in Escherichia coli, purification, and spectroscopic characterization of two mutant Bet v 1 proteins.
Boehm M(1), Rösch P.
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| 10722049 | Biol Chem. 2000 Jan;381(1):39-47.
Engineering, purification and applications of His-tagged recombinant antibody fragments with specificity for the major birch pollen allergen, bet v1.
Flicker S(1), Laffer S, Steinberger P, Alhani B, Zhu Y, Laukkanen ML, Keinänen K, Kraft D, Valenta R.
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| 12834978 | J Biochem Biophys Methods. 2003 Jun 30;56(1-3):219-32.
Size exclusion chromatography as a tool for quality control of recombinant allergens and hypoallergenic variants.
Weber B(1), Slamal H, Suck R.
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| 15722633 | Int Arch Allergy Immunol. 2005 Mar;136(3):239-49. Epub 2005 Feb 16.
Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.
Batard T(1), Didierlaurent A, Chabre H, Mothes N, Bussières L, Bohle B, Couret MN, Ball T, Lemoine P, Focks Tejkl M, Chenal A, Clément G, Dupont F, Valent P, Krauth MT, André C, Valenta R, Moingeon P.
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| 17912007 | Int Arch Allergy Immunol. 2008;145(3):193-206. Epub 2007 Oct 2.
Characterization of a hypoallergenic recombinant Bet v 1 variant as a candidate for allergen-specific immunotherapy.
Kahlert H(1), Suck R, Weber B, Nandy A, Wald M, Keller W, Cromwell O, Fiebig H.
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| 17979095 | Mol Nutr Food Res. 2007 Dec;51(12):1527-36.
Purification and characterization of natural Bet v 1 from birch pollen and related allergens from carrot and celery.
Bollen MA(1), Garcia A, Cordewener JH, Wichers HJ, Helsper JP, Savelkoul HF, van Boekel MA.
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| 19183416 | Allergy. 2009 Jul;64(7):1038-45. doi: 10.1111/j.1398-9995.2009.01957.x. Epub 2009 Jan 31.
Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v 1.0101 as biological reference preparation.
Himly M(1), Nony E, Chabre H, Van Overtvelt L, Neubauer A, van Ree R, Buchheit KH, Vieths S, Moingeon P, Ferreira F.
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| 19257882 | BMC Plant Biol. 2009 Mar 3;9:24. doi: 10.1186/1471-2229-9-24.
Characterization of PR-10 genes from eight Betula species and detection of Bet v 1 isoforms in birch pollen.
Schenk MF(1), Cordewener JH, America AH, Van't Westende WP, Smulders MJ, Gilissen LJ.
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| 19345650 | J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Aug 15;877(24):2420-7. doi: 1016/j.jchromb.2009.03.020. Epub 2009 Mar 18.
High throughput screening of mixed-mode sorbents and optimisation using pre-packed lab-scale columns for the purification of the recombinant allergen rBet v 1a.
Brenac Brochier V(1), Chabre H, Lautrette A, Ravault V, Couret MN, Didierlaurent A, Moingeon P.
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| 22348091 | PLoS One. 2012;7(2):e31483. doi: 10.1371/journal.pone.0031483. Epub 2012 Feb 14.
Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells.
Karle AC(1), Oostingh GJ, Mutschlechner S, Ferreira F, Lackner P, Bohle B, Fischer GF, Vogt AB, Duschl A.
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| 23229638 | Immunol Cell Biol. 2013 Feb;91(2):167-72. doi: 10.1038/icb.2012.70. Epub 2012 Dec
Different modes of IgE binding to CD23 revealed with major birch allergen, Bet v 1-specific monoclonal IgE.
Reginald K(1), Eckl-Dorna J, Zafred D, Focke-Tejkl M, Lupinek C, Niederberger V, Keller W, Valenta R.
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| 24037615 | Anal Bioanal Chem. 2013 Nov;405(27):8945-9. doi: 10.1007/s00216-013-7324-0. Epub 2013 Sep 14.
Determination of nitration degrees for the birch pollen allergen Bet v 1.
Selzle K(1), Ackaert C, Kampf CJ, Kunert AT, Duschl A, Oostingh GJ, Pöschl U.
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| 24517313 | J Proteome Res. 2014 Mar 7;13(3):1570-7. doi: 10.1021/pr401078h. Epub 2014 Feb
Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents.
Reinmuth-Selzle K(1), Ackaert C, Kampf CJ, Samonig M, Shiraiwa M, Kofler S, Yang H, Gadermaier G, Brandstetter H, Huber CG, Duschl A, Oostingh GJ, Pöschl U.
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| 25126882 | PLoS One. 2014 Aug 15;9(8):e104520. doi: 10.1371/journal.pone.0104520. eCollection 2014.
The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.
Ackaert C(1), Kofler S(1), Horejs-Hoeck J(1), Zulehner N(2), Asam C(3), von Grafenstein S(4), Fuchs JE(4), Briza P(1), Liedl KR(4), Bohle B(2), Ferreira F(3), Brandstetter H(1), Oostingh GJ(1), Duschl A(1).
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| 25846209 | Allergy. 2015 Jul;70(7):795-804. doi: 10.1111/all.12622. Epub 2015 Apr 20.
Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patients.
Nony E(1), Bouley J(1), Le Mignon M(1), Lemoine P(1), Jain K(1), Horiot S(1), Mascarell L(1), Pallardy M(2), Vincentelli R(3), Leone P(3), Roussel A(3), Batard T(1), Abiteboul K(1), Robin B(1), de Beaumont O(1), Arvidsson M(4), Rak S(4), Moingeon P(1).
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| 28494467 | Int Arch Allergy Immunol. 2017;173(1):44-50. doi: 10.1159/000471852. Epub 2017 May 12.
Expression and Characterization of Functional Recombinant Bet v 1.0101 in the Chloroplast of Chlamydomonas reinhardtii.
Hirschl S(1), Ralser C, Asam C, Gangitano A, Huber S, Ebner C, Bohle B, Wolf M, Briza P, Ferreira F, Griesbeck C, Wallner M.
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| 29171882 | Allergy. 2018 May;73(5):1032-1040. doi: 10.1111/all.13364. Epub 2017 Dec 12.
Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1.
Brier S(1), Le Mignon M(1), Jain K(1), Lebrun C(1), Peurois F(1), Kellenberger C(2), Bordas-Le Floch V(1), Mascarell L(1), Nony E(1), Moingeon P(1).
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| 30850635 | Sci Rep. 2019 Mar 8;9(1):4006. doi: 10.1038/s41598-019-39798-8.
Fusion proteins consisting of Bet v 1 and Phl p 5 form IgE-reactive aggregates with reduced allergenic activity.
Najafi N(1), Hofer G(2), Gattinger P(1), Smiljkovic D(3), Blatt K(3), Selb R(4), Stoecklinger A(5), Keller W(2), Valent P(3), Niederberger V(4), Thalhamer J(5), Valenta R(1)(6)(7), Flicker S(8).
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