References/Publications for Mass spectrometry (MS) of Alt a 6

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34829261
J Fungi (Basel). 2021 Nov 16;7(11). pii: 974. doi: 10.3390/jof7110974.

Changes in the Sensitization Pattern to Alternaria alternata Allergens in
Patients Treated with Alt a 1 Immunotherapy.

Rodríguez D(1), Tabar AI(2)(3), Castillo M(1), Martínez-Gomariz M(1), Dobski
IC(1), Palacios R(1).


4% of the patients recognized Alt a 1. The percentage of recognition for Alt
a 3, Alt a 4, and/or Alt a 6, Alt a 7, Alt a 8, Alt a 10 and/or Alt a 15 was
6%, 21.9%, 12.5%, 12.5%, and 12.5% respectively. Of the 64 patients, 45 (70.3%)
only recognized Alt a 1 among the allergens present in the A. alternata extract.
Immunotherapy with Alt a 1 desensitizes treated patients, reducing their symptoms
and medication consumption through the elimination of Alt a 1 sensitization,
which is no longer present in the immunoblotting of some patients. There may be
gender differences in the pattern of sensitization to A. alternata allergens,
among others.

DOI: 10.3390/jof7110974
PMCID: PMC8618185
PMID: 34829261